Evidence map›Paper›PMID 33606692›Full record

ArticlePloS one2021

The syndemic effects of mental ill health, household hunger, and intimate partner violence on adherence to antiretroviral therapy among pregnant women living with HIV in Yaoundé, Cameroon.

Evette Cordoba, Angela M Parcesepe, John A Gallis, Jennifer Headley, Claudian Soffo, Berenger Tchatchou, John Hembling, Joy Noel Baumgartner

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Evette CordobaDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Angela M ParcesepeDepartment of Maternal and Child Health, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.ORCID 0000-0002-4321-125X
John A GallisDuke Global Health Institute, Duke University, Durham, North Carolina, United States of America.
Jennifer HeadleyDuke Global Health Institute, Duke University, Durham, North Carolina, United States of America.
Claudian SoffoConsultant, Yaoundé, Cameroon.
Berenger TchatchouCatholic Relief Services, N'Djamena, Chad.
John HemblingCatholic Relief Services, Baltimore, Maryland, United States of America.
Joy Noel BaumgartnerDuke Global Health Institute, Duke University, Durham, North Carolina, United States of America.
Duke University · USCatholic Relief Services · USUniversity of North Carolina at Chapel Hill · US

Funding

Support for QA/QC for Prior Approval ProcessUL1TR002553 · NCATS · DUKE UNIVERSITY · PI LI, JENNIFER S, MCNAMARA, JAMES O. · 2018 to 2023
$58.5M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Understanding and addressing mental and substance use disorders among people living with HIV in low-resource settingsK01MH114721 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PARCESEPE, ANGELA · 2018 to 2022
$766k
NCATS NIH HHS UL1 TR002553NICHD NIH HHS P2C HD050924NIMH NIH HHS K01 MH114721
6 · The paper itself

Abstract

backgroundThis research advances understanding of interrelationships among three barriers to adherence to antiretroviral therapy (ART) among pregnant women living with HIV (WLWH) in Cameroon: probable common mental disorders (CMD), intimate partner violence (IPV), and hunger.

methodsThe sample included 220 pregnant WLWH in Cameroon. Multivariable modified Poisson regression was conducted to assess the relationship between IPV, hunger, and CMD on ART adherence.

resultsAlmost half (44%) of participants recently missed/mistimed an ART dose. Probable CMD was associated with greater risk of missed/mistimed ART dose (aRR 1.5 [95% CI 1.1, 1.9]). Hunger was associated with greater risk of missed/mistimed ART dose among those who reported IPV (aRR 1.9 [95% CI 1.2, 2.8]), but not among those who did not (aRR 0.8 [95% CI 0.2, 2.3]).

conclusionSuboptimal ART adherence, CMD, and IPV were common among pregnant WLWH in Cameroon. Pregnant WLWH experiencing IPV and hunger may be especially vulnerable to suboptimal ART adherence.

Indexed as

HIV InfectionsHungerIntimate Partner ViolenceMedication AdherenceMental HealthPregnant PeopleAdolescentAdultAnti-HIV AgentsCameroonCross-Sectional StudiesFemaleHumansPregnancySyndemicYoung AdultAnti-HIV Agents

Identifiers

PMID33606692
PMCPMC7894814
OpenAlexW3129584666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.