Evidence map›Paper›PMID 33606240›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

In Vivo Protein Lifetime Measurements Across Multiple Organs in the Zebrafish.

Sunit Mandad, Gudrun Kracht, Eugenio F Fornasiero

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sunit MandadDepartment of Neuro- and Sensory Physiology & Center for Biostructural Imaging of Neurodegeneration (BIN), Institut für Neuro- und Sinnesphysiologie, University Medical Center Göttingen, Göttingen, Germany.
Gudrun KrachtDepartment of Developmental Biochemistry, Zentrum Biochemie, University Medical Center Göttingen, Göttingen, Germany.
Eugenio F FornasieroDepartment of Neuro- and Sensory Physiology & Center for Biostructural Imaging of Neurodegeneration (BIN), Institut für Neuro- und Sinnesphysiologie, University Medical Center Göttingen, Göttingen, Germany. efornas@gwdg.de.
Universitätsmedizin Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein production and degradation are tightly regulated to prevent cellular structures from accumulating damage and to allow their correct functioning. A key aspect of this regulation is the protein half-life, corresponding to the time in which half of a specific protein population is exchanged with respect to its initial state. Proteome-wide techniques to investigate protein half-lives in vivo are emerging. Recently, we have established and thoroughly tested a metabolic labeling approach using

Indexed as

Amino AcidsAnimalsFemaleHalf-LifeIsotope LabelingLysineMaleProteomeProteomicsZebrafishZebrafish ProteinsAmino AcidsLysineProteomeZebrafish ProteinsBoxCarMetabolic labelingProtein lifetimeProtein mass spectrometryProtein turnoverSILAC

Identifiers

PMID33606240
OpenAlexW3131640024

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.