ReviewCurrent HIV/AIDS reports2021
Undernutrition and HIV Infection in Sub-Saharan Africa: Health Outcomes and Therapeutic Interventions.
Review in Current HIV/AIDS reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Prevalence and associated factors of undernutrition among adults living with HIV in ethiopia: a systematic review and meta-analysis.Journal of health, population, and nutrition · 2025Pooled it
- The Impact of Undernutrition and Anemia on HIV-Related Mortality Among Children on ART in Sub-Saharan Africa: A Systematic Review and Meta-Analysis.Journal of epidemiology and global health · 2024Pooled it
- Hepatic Steatosis in People With Chronic Hepatitis B in Africa: Prevalence, Correlates, and Clinical Significance.Journal of viral hepatitis · 2026Article
- Cross-Lagged Dyadic Associations of Food Insecurity and Depressive Symptoms among Couples Living with HIV and Cardiometabolic Disorders in Malawi.Current developments in nutrition · 2026Article
- Causes and Contributing Factors of In-Hospital and Post-Discharge Mortality Among Patients With Severe Acute Respiratory Infection in Low- and Middle-Income Countries: A Scoping Review.Health science reports · 2026Article
- Prevalence and socio-demographic factors associated with undernutrition among HIV-positive women of reproductive age in Mahama refugee camp, Rwanda.BMC public health · 2026Article
- Prevalence of undernutrition among children on anti-retroviral therapy at comprehensive specialized hospital: a cross-sectional study.Scientific reports · 2026Article
- Linkage to TB and HIV care for persons who smoke illicit drugs: a prospective cohort study.IJTLD open · 2026Article
- Article
- Nutritional status and functional capacity among people living with HIV in routine care: a retrospective cohort study.Frontiers in public health · 2026Article
- Geospatial Mapping of Pediatric Febrile Illness in Uganda to Inform Precision Public Health Interventions.Open forum infectious diseases · 2026Article
- Combined antiretroviral therapy with low- or normal-protein, high-calorie diets appears to induce significant deleterious electrocardiographic changes in a rodent model.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026Article
- Bilateral Pathological Femoral Fractures Secondary to Long-Term Tenofovir Disoproxil Fumarate-Induced Osteomalacia in a Woman Living with HIV: A Case Report.International medical case reports journal · 2026Article
- Association of dietary patterns with anxiety and depression symptoms in people living with HIV: a population-based cross-sectional study from China.BMC public health · 2025Article
- Under-nutrition and its associated factors among adult second-line antiretroviral treatment users in Northern Ethiopia.BMC public health · 2025Article
- Magnitude, Determinants, and Coping Strategies of Food Insecurity Among People Living With HIV/AIDS in Eastern Ethiopia.AIDS research and treatment · 2025Article
- Retention on antiretroviral therapy and drivers of lost-to-follow up in the Central African Republic: a longitudinal analysis.Journal of the International AIDS Society · 2024Article
- A qualitative study to inform the development of a decision support tool for the diagnosis of pulmonary tuberculosis in Tigray, Ethiopia.BMC medical informatics and decision making · 2024Article
- Food insecurity and unemployment as mediators of the relationship between the COVID-19 pandemic and psychological well-being in young South Africans with HIV.BMC public health · 2024Article
- The COVID-19 pandemic, food insecurity, and psychosocial well-being in young South Africans newly diagnosed with HIV: a mediation analysis.Research square · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
purpose of reviewSub-Saharan Africa (SSA) is disproportionately burdened by the twin epidemics of food insecurity and HIV infection, and protein-calorie undernutrition is common among persons with HIV (PWH) initiating antiretroviral therapy (ART) in the region. In this review, we discuss the intersection of HIV infection and undernutrition, health outcomes among undernourished PWH starting ART, and the demonstrated and potential benefits of therapeutic interventions such as micro/macronutrient supplementation and pharmacological agents. RECENT
findingsA low body mass index (BMI), used as a general indicator of poor nutrition in most studies, is associated with impaired immune recovery and increased mortality in the early ART period. The increased risk of mortality is multifactorial, and contributors include undernutrition-related immune system dysfunction, increased susceptibility to opportunistic infections, and metabolic and cardiovascular dysregulation. Clinical trials of micro/macronutrient supplementary feeding, appetite stimulants (hormones and anabolic agents), and recombinant adipokines have shown a benefit for weight gain and metabolic health, but there are few data on mortality or immune recovery. A substantial proportion of PWH in SSA are undernourished, and undernutrition contributes to an increased risk of mortality and other adverse health outcomes. To date, there have been few prospective trials of nutritional supplementation and/or pharmacologic therapy among undernourished PWH in SSA, though findings from other settings suggest a potential benefit in this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.