Evidence map›Paper›PMID 33606189›Full record

ArticleJournal of muscle research and cell motility2021

Voluntary exercise does not improve muscular properties or functional capacity during C26-induced cancer cachexia in mice.

Charlotte Hiroux, Sebastiaan Dalle, Katrien Koppo, Peter Hespel

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Journal of muscle research and cell motility, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Charlotte HirouxExercise Physiology Research Group, Department of Movement Sciences, KU Leuven, Tervuursevest 101, box 1500, 3001, Leuven, Belgium.ORCID 0000-0001-8345-0119
Sebastiaan DalleExercise Physiology Research Group, Department of Movement Sciences, KU Leuven, Tervuursevest 101, box 1500, 3001, Leuven, Belgium.ORCID 0000-0001-5734-3993
Katrien KoppoExercise Physiology Research Group, Department of Movement Sciences, KU Leuven, Tervuursevest 101, box 1500, 3001, Leuven, Belgium.ORCID 0000-0002-6022-1097
Peter HespelExercise Physiology Research Group, Department of Movement Sciences, KU Leuven, Tervuursevest 101, box 1500, 3001, Leuven, Belgium. peter.hespel@kuleuven.be.ORCID 0000-0003-1283-2229
KU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exercise training is considered as a potential intervention to counteract muscle degeneration in cancer cachexia. However, evidence to support such intervention is equivocal. Therefore, we investigated the effect of exercise training, i.e. voluntary wheel running, on muscle wasting, functional capacity, fiber type composition and vascularization during experimental cancer cachexia in mice. Balb/c mice were injected with PBS (CON) or C26 colon carcinoma cells to induce cancer cachexia (C26). Mice had free access to a running wheel in their home cage (CON

Indexed as

CachexiaColonic NeoplasmsAnimalsMiceMice, Inbred BALB CMotor ActivityMuscle, SkeletalMuscular AtrophyCancer cachexiaCapillary densityFiber type compositionMuscle atrophyMuscle functionalityVoluntary wheel running

Identifiers

PMID33606189
OpenAlexW3129444549

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.