ArticleNeuroscience bulletin2021
Decoding Cortical Glial Cell Development.
Open access · hybridAbstract read
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Article in Neuroscience bulletin, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.
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0cells of the map it votes in
81citing papers in PubMed
9.7field-weighted citation impact, top 1% of its field
What it found
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Who cites it
81 citing papers in PubMed, 115 citations in OpenAlex.
- Article
- Glial Cell Niche Induces Astrocytic Differentiation of NSCs via the BMP4-Smad1/5/8 Signaling Pathway.International journal of molecular sciences · 2026Article
- Ascl1 promotes OPC specification across species and central nervous system regions and its gliogenic function is regulated by phosphorylation.Developmental biology · 2026Article
- Delayed astrocyte development impairs Sema6a-Plxna2/4-mediated astrocyte-neuron crosstalk and causes depressive-like behavior.Nature communications · 2026Article
- Molecular signatures and lineage diversification of neurogenic and gliogenic radial glia in the gyrencephalic ferret cortex.Communications biology · 2026Article
- Diversity of cortical progenitors directs neuronal layer formation and regional glial patterning.Stem cell reports · 2026Article
- Article
- CellPolaris: Transfer Learning for Gene Regulatory Network Construction to Guide Cell State Transitions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Integrated ERK-PKA-YAP/TAZ-SHH Signaling Orchestrates Cortical Radial Glia Identity and Lineage Diversification.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Impact of Prenatal Alcohol Exposure on Cerebral Cortex Development.Advances in experimental medicine and biology · 2026Review
- Special characteristics of human astrocytes and their roles in brain homeostasis.Neuroscience applied · 2026Review
- Molecular signatures and lineage diversification of neurogenic and gliogenic radial glia in the gyrencephalic ferret cortex.Research square · 2025Article
- Olig1/2 Orchestrates Progenitor Cell Fates during Mammalian Cortical Gliogenesis and Gliomagenesis.Nature communications · 2025Article
- Mouse cortical cellular diversification through lineage progression of radial glia.Genes & development · 2025Article
- Article
- Dissecting Gene Regulatory Networks Governing Human Cortical Cell Fate.bioRxiv : the preprint server for biology · 2025Article
- NR3C1-mediated epigenetic regulation suppresses astrocytic immune responses in mice.Nature communications · 2025Article
- Dual lineage origins contribute to neocortical astrocyte diversity.Nature communications · 2025Article
- Cell fate acquisition and reprogramming by the proneural transcription factor ASCL1.Open biology · 2025Review
- RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 4 institutions in 2 countries.
Xiaosu Li *State Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontiers Center for Brain Science, Department of Neurology, Institute for Translational Brain Research, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Guoping Liu *State Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontiers Center for Brain Science, Department of Neurology, Institute for Translational Brain Research, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Lin Yang *State Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontiers Center for Brain Science, Department of Neurology, Institute for Translational Brain Research, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Zhenmeiyu Li *State Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontiers Center for Brain Science, Department of Neurology, Institute for Translational Brain Research, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Zhuangzhi ZhangState Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontiers Center for Brain Science, Department of Neurology, Institute for Translational Brain Research, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Zhejun XuState Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontiers Center for Brain Science, Department of Neurology, Institute for Translational Brain Research, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Yuqun CaiState Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontiers Center for Brain Science, Department of Neurology, Institute for Translational Brain Research, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Heng DuState Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontiers Center for Brain Science, Department of Neurology, Institute for Translational Brain Research, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Zihao SuState Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontiers Center for Brain Science, Department of Neurology, Institute for Translational Brain Research, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Ziwu WangState Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontiers Center for Brain Science, Department of Neurology, Institute for Translational Brain Research, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Yangyang DuanState Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontiers Center for Brain Science, Department of Neurology, Institute for Translational Brain Research, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Haotian ChenState Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontiers Center for Brain Science, Department of Neurology, Institute for Translational Brain Research, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Zicong ShangState Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontiers Center for Brain Science, Department of Neurology, Institute for Translational Brain Research, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Yan YouState Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontiers Center for Brain Science, Department of Neurology, Institute for Translational Brain Research, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Qi ZhangState Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontiers Center for Brain Science, Department of Neurology, Institute for Translational Brain Research, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Miao HeState Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontiers Center for Brain Science, Department of Neurology, Institute for Translational Brain Research, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Bin ChenDepartment of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA, 95064, USA.
Zhengang YangState Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontiers Center for Brain Science, Department of Neurology, Institute for Translational Brain Research, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. yangz@fudan.edu.cn.
State Key Laboratory of Medical NeurobiologyFudan University · CNZhongshan Hospital · CNUniversity of California, Santa Cruz · US
Funding
Lineage Progression of Cortical Neural Stem CellsR01NS089777 · NINDS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI CHEN, BIN · 2015 to 2025
$4.7MTranscriptional regulation of neuronal identity and connectivityR01MH094589 · NIMH · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI CHEN, BIN · 2011 to 2021
$3.7MNIMH NIH HHS R01 MH094589NINDS NIH HHS R01 NS089777
Abstract
Mouse cortical radial glial cells (RGCs) are primary neural stem cells that give rise to cortical oligodendrocytes, astrocytes, and olfactory bulb (OB) GABAergic interneurons in late embryogenesis. There are fundamental gaps in understanding how these diverse cell subtypes are generated. Here, by combining single-cell RNA-Seq with intersectional lineage analyses, we show that beginning at around E16.5, neocortical RGCs start to generate ASCL1
Indexed as
Neural Stem CellsNeurogenesisAnimalsCell DifferentiationMiceNeurogliaOligodendrogliaASCL1AstrocyteCerebral cortexEGFRIntermediate progenitor cellOlfactory bulb interneuronOLIG2OligodendrocyteRadial glial cell
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.