Evidence map›Paper›PMID 33606155›Full record

ArticleInternational urology and nephrology2021

Effect of prostatic apex shape (Lee types) and urethral sphincter length in preoperative MRI on very early continence rates after radical prostatectomy.

Mike Wenzel, Felix Preisser, Matthias Mueller, Lena H Theissen, Maria N Welte, Benedikt Hoeh, Clara Humke, Simon Bernatz, Boris Bodelle, Christoph Würnschimmel and 9 more

Open access · hybridAbstract read
In one paragraph

Article in International urology and nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 2 countries.

Mike Wenzel *Department of Urology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany. Mike.Wenzel@kgu.de.ORCID http://orcid.org/0000-0002-4338-0889
Felix Preisser *Department of Urology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Matthias MuellerDepartment of Urology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Lena H TheissenDepartment of Urology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Maria N WelteDepartment of Urology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Benedikt HoehDepartment of Urology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Clara HumkeDepartment of Urology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Simon BernatzDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt am Main, Germany.
Boris BodelleDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt am Main, Germany.
Christoph WürnschimmelCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montreal Health Center, Montreal, QC, Canada.
Derya TilkiMartini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
Hartwig HulandMartini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
Markus GraefenMartini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
Frederik C RoosDepartment of Urology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Andreas BeckerDepartment of Urology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Pierre I KarakiewiczCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montreal Health Center, Montreal, QC, Canada.
Felix K H ChunDepartment of Urology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Luis A KluthDepartment of Urology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Philipp MandelDepartment of Urology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Goethe University Frankfurt · DEUniversität Hamburg · DEUniversité de Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo test the effect of anatomic variants of the prostatic apex overlapping the membranous urethra (Lee type classification), as well as median urethral sphincter length (USL) in preoperative multiparametric magnetic resonance imaging (mpMRI) on the very early continence in open (ORP) and robotic-assisted radical prostatectomy (RARP) patients.

methodsIn 128 consecutive patients (01/2018-12/2019), USL and the prostatic apex classified according to Lee types A-D in mpMRI prior to ORP or RARP were retrospectively analyzed. Uni- and multivariable logistic regression models were used to identify anatomic characteristics for very early continence rates, defined as urine loss of ≤ 1 g in the PAD-test.

resultsOf 128 patients with mpMRI prior to surgery, 76 (59.4%) underwent RARP vs. 52 (40.6%) ORP. In total, median USL was 15, 15 and 10 mm in the sagittal, coronal and axial dimensions. After stratification according to very early continence in the PAD-test (≤ 1 g vs. > 1 g), continent patients had significantly more frequently Lee type D (71.4 vs. 54.4%) and C (14.3 vs. 7.6%, p = 0.03). In multivariable logistic regression models, the sagittal median USL (odds ratio [OR] 1.03) and Lee type C (OR: 7.0) and D (OR: 4.9) were independent predictors for achieving very early continence in the PAD-test.

conclusionPatients' individual anatomical characteristics in mpMRI prior to radical prostatectomy can be used to predict very early continence. Lee type C and D suggest being the most favorable anatomical characteristics. Moreover, longer sagittal median USL in mpMRI seems to improve very early continence rates.

Indexed as

Multiparametric Magnetic Resonance ImagingProstatectomyAgedAnatomic VariationHumansMaleMiddle AgedOrgan SizePostoperative ComplicationsPreoperative PeriodProstateProstatic NeoplasmsRetrospective StudiesTime FactorsUrethraUrinary IncontinenceLee type, functional outcomeORPPAD-testRARP

Identifiers

PMID33606155
PMCPMC8192356
OpenAlexW3131693252

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.