ArticleEuropean radiology2021
The validity, reliability, and reviewer acceptance of VI-RADS in assessing muscle invasion by bladder cancer: a multicenter prospective study.
Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The accuracy of Vesical Imaging-Reporting and Data System (VI-RADS): an updated comprehensive multi-institutional, multi-readers systematic review and meta-analysis from diagnostic evidence into future clinical recommendations.World journal of urology · 2022Pooled it
- Diagnostic accuracy of vesical imaging-reporting and data system (VI-RADS) for the detection of muscle-invasive bladder cancer: a meta-analysis.Abdominal radiology (New York) · 2022Pooled it
- A Quantitative Modification of VI-RADS for Bladder Cancer at the Ureteral Orifice: A Reader Study on MRI With Varying Experience Levels.Journal of magnetic resonance imaging : JMRI · 2026Article
- Added value of synthetic MRI in refining biparametric MRI VI-RADS for predicting muscle-invasive bladder cancer.Abdominal radiology (New York) · 2026Article
- What's next for VI-RADS? Updates and future perspectives from the ACR VI-RADS steering committee.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Review
- Clinical value of VI-RADS score in predicting repeat transurethral resection in primary bladder cancer: a prospective observational study.BMC urology · 2026Observational
- Assessment of multi-parameter dual-energy CT in predicting muscle invasion in bladder cancer: comparison with VI-RADS.Insights into imaging · 2026Article
- The clinical study of preoperative normalized apparent diffusion coefficient of 3.0-T MRI in predicting muscular invasion of bladder cancer.BMC medical imaging · 2025Article
- Precise vesical wall staging of bladder cancer in the era of precision medicine: has it been fulfilled?Abdominal radiology (New York) · 2025Review
- Perspective on the use of optics in bladder cancer detection and diagnosis.Journal of biomedical optics · 2025Review
- A Machine Learning Model Based on Multi-Phase Contrast-enhanced CT for the Preoperative Prediction of the Muscle-Invasive Status of Bladder Cancer.Current medical imaging · 2025Article
- Implementing VIRADS score for image-guided assessment of muscle invasiveness in bladder cancer pre-TURBT: An updated meta-analysis.Arab journal of urology · 2025Review
- [Application of Magnetic Resonance Imaging Report Combined With VI-RADS Bi-Parametric and Multi-Parametric Scoring Systems in Bladder Cancer Diagnosis].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024Article
- The role of VI-RADS scoring criteria for predicting oncological outcomes in bladder cancer.World journal of urology · 2024Article
- VI-RADS scoring system for predicting 1- to 5-year recurrence of bladder cancer.European radiology · 2024Article
- Clinical application of bladder MRI and the Vesical Imaging-Reporting and Data System.Nature reviews. Urology · 2024Review
- Progress of Multiparameter Magnetic Resonance Imaging in Bladder Cancer: A Comprehensive Literature Review.Diagnostics (Basel, Switzerland) · 2024Review
- Vesical imaging reporting and data system (VI-RADS) could predict the survival of bladder-cancer patients who received radical cystectomy.Scientific reports · 2023Article
- Article
- A machine learning model based on MRI for the preoperative prediction of bladder cancer invasion depth.European radiology · 2023Article
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Authors and funding
13 authors.
Funding
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Abstract
objectiveTo assess diagnostic validity and reliability of VI-RADS in predicting muscle invasion by bladder cancer (BCa) and evaluate reviewer acceptance of VI-RADS for clinical routine.
methodsA prospective multicenter study enrolled 331 patients with suspected/untreated BCa who underwent preoperative multiparametric MRI examination (mp-MRI) of the urinary bladder. Four experienced radiologists independently evaluated all mp-MRI using VI-RADS. The diagnostic validity of VI-RADS for predicting muscle invasion by BCa was calculated using histopathology of the first transurethral resection bladder tumor (TURBT) and second TURBT as the reference standards. The kappa statistics (κ) were applied to assess the interreader agreement (IRA). Reviewer acceptance was evaluated with questionnaires.
resultsThe risk of muscle invasion in VI-RADS 2, 3, 4, and 5 after the first and second TURBT was 21.8%, 45.8%, 69.6%, and 96.4% and 24.4%, 58.3%, 87%, and 99.2%, respectively. The overall diagnostic validity of VI-RADS was high. The optimal cut-off value for predicting muscle invasion after first TURBT was > VI-RADS 3 (sensitivity = 84.1% and specificity = 92.3%), and after second TURBT was > VI-RADS 2 (sensitivity = 89.9% and specificity = 90.1%). VI-RADS categorization showed a very good IRA (κ = 0.93). Reviewers fully agreed with the statement, "The application of structured reporting of bladder tumor should be encouraged" (score = 20).
conclusionsVI-RADS showed high diagnostic validity and reliability for predicting muscle invasion by BCa, especially VI-RADS 4 and 5. However, VI-RADS 2 and 3 require further modifications to enhance their diagnostic validity. VI-RADS is highly encouraged to be used in daily practice. KEY POINTS: • VI-RADS showed high diagnostic validity and reliability in predicting BCa muscle invasion, especially VI-RADS 4 and 5. • In VI-RADS 2 and 3, we observed a notable percentage of BCa with muscle invasion and this would require further modifications to enhance the diagnostic validity for these scores. • Overall VI-RADS is well-accepted by radiologists who recommend it for daily practice.
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