Observational studyJapanese journal of ophthalmology2021
Clinicopathologic analysis of 32 ciliary body tumors.
Observational study in Japanese journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- A case of ciliary body leiomyoma penetrating the sclera.American journal of ophthalmology case reports · 2025Article
- A case report: iridociliary melanocytoma associated with secondary glaucoma.Diagnostic pathology · 2025Article
- Ultrasonographic features of ciliary body mesectodermal leiomyoma.International journal of ophthalmology · 2025Article
- Local resection via partial lamellar sclerouvectomy for ciliary body tumors - a case series.BMC ophthalmology · 2024Article
- Hidden peril: Large ciliary body melanoma imitating cataract in a cardiac patient.Romanian journal of ophthalmologyArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo describe the demographic profile, clinical and histopathologic features, and treatment of ciliary body tumors. STUDY
designRetrospective, observational case series.
methodsThirty-two patients (32 eyes) with ciliary body tumors diagnosed histopathologically at Tokyo Medical University Hospital between 1994 and 2017 were retrospectively reviewed.
resultsThe patients' mean age at diagnosis was 45.4 ± 17.0 (range, 14-87) years. Ten of the patients were male, and 22, female. Twenty-four cases (75%) were benign tumors, comprising 9 melanocytomas, 7 adenomas, 4 mesectodermal leiomyomas, 2 leiomyomas, and 2 other tumors; and 8 cases (25%) were malignant tumors, comprising 6 melanomas and 2 low-grade adenocarcinomas. Local resection of the tumor was performed in 20 patients, including 3 cases of melanoma and 2 cases of adenocarcinoma. Enucleation was initially performed in 3 cases of melanoma, 1 case of melanocytoma with iris melanoma, and 2 cases of benign tumors difficult to differentiate clinically from melanoma. In the 17 patients who underwent local resection and were followed for at least 3 years, the outcome was best-corrected visual acuity better than 0.1 logMAR in 8 patients (47%), but hand motions in 2 patients (12%).
conclusionsMelanocytoma and adenoma of the ciliary epithelium were the major ciliary body tumors found in this study. Management of ciliary body tumors with accurate clinical diagnosis remains challenging because of the anatomic characteristics and clinical similarities to melanoma in the majority of the cases.
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