Evidence map›Paper›PMID 33606085›Full record

ArticleArchives of orthopaedic and trauma surgery2022

Perioperative blood transfusions in hip and knee arthroplasty: a retrospective assessment of combined risk factors.

Hans-Christoph Erben, Florian Hess, JoEllen Welter, Nicole Graf, Marc P Steurer, Thomas A Neff, Ralph Zettl, Alexander Dullenkopf

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Article in Archives of orthopaedic and trauma surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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6citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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6 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Hans-Christoph ErbenInstitute for Anesthesia and Intensive Care Medicine, Spital Thurgau, 8501, Frauenfeld, Switzerland.
Florian HessDepartment of Orthopedic Surgery and Traumatology, Spital Thurgau, Frauenfeld, Switzerland.
JoEllen WelterInstitute for Anesthesia and Intensive Care Medicine, Spital Thurgau, 8501, Frauenfeld, Switzerland.
Nicole GrafGraf Biostatistics, Winterthur, Switzerland.
Marc P SteurerDepartment of Anesthesia and Perioperative Care, University of California, San Francisco, USA.
Thomas A NeffDepartment of Anesthesia and Intensive Care Medicine, Spital Thurgau, Münsterlingen, Switzerland.
Ralph ZettlDepartment of Orthopedic Surgery and Traumatology, Spital Thurgau, Frauenfeld, Switzerland.
Alexander DullenkopfInstitute for Anesthesia and Intensive Care Medicine, Spital Thurgau, 8501, Frauenfeld, Switzerland. alexander.dullenkopf@stgag.ch.ORCID http://orcid.org/0000-0002-1456-6457

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAccurate identification of patients at risk of blood transfusion can reduce complications and improve institutional resource allocation. Probabilistic models are used to detect risk factors and formulate patient blood management strategies. Whether these predictors vary among institutions is unclear. We aimed to identify risk factors among our patients who underwent total hip (THA) or knee (TKA) arthroplasty, and combine these predictors to improve our model. MATERIALS AND

methodsWe retrospectively assessed risk factors among 531 adults who underwent elective THA or TKA from January 2016 to November 2018. Using relevant surgical and patient characteristics gathered from electronic medical records, we conducted univariable and multivariable analyses. For our logistic regression model, we measured the impact of independent variables (age, gender, operation type (THA or TKA) and preoperative hemoglobin concentration) on the need for a transfusion.

resultsOf the 531 patients, 321 had THA (uncemented) and 210 had TKA. For the selected period, our transfusion rate of 8.1% (10.6% THA and 4.3% TKA) was low. Univariable analyses showed that lower BMI (p < 0.001) was associated with receiving a transfusion. Important factors identified through logistic regression analyses were age (estimated effect of an interquartile range increase in age: OR 3.89 [CI 95% 1.96-7.69]), TKA (OR - 0.77 [CI 95% - 1.57-0.02]), and preoperative hemoglobin levels (estimated effect of interquartile range increase in hemoglobin: OR 0.47 [CI 95% 0.31-0.71]). Contrary to findings from previous reports, gender was not associated with transfusion.

conclusionsPreviously published predictors such as advanced age, low preoperative hemoglobin, and procedure type (THA) were also identified in our analysis. However, gender was not a predictor, and BMI showed the potential to influence risk. We conclude that, when feasible, the determination of site-specific transfusion rates and combined risk factors can assist practitioners to customize care according to the needs of their patient population. LEVEL OF EVIDENCE: Level 3, retrospective cohort study.

Indexed as

Arthroplasty, Replacement, HipArthroplasty, Replacement, KneeAdultBlood TransfusionHemoglobinsHumansRetrospective StudiesRisk FactorsHemoglobinsBlood transfusionHip arthroplastyKnee arthroplastyPatient blood managementRisk assessment

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.