Evidence map›Paper›PMID 33606074›Full record

ArticleInternational journal of colorectal disease2021

Oral antibiotic bowel decontamination in open and laparoscopic sigmoid resections for diverticular disease.

Ulrich Wirth, Josefine Schardey, Thomas von Ahnen, Petra Zimmermann, Florian Kühn, Jens Werner, Hans Martin Schardey, Bettina M Rau, Julia Gumpp

Open access · hybridAbstract read
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In one paragraph

Article in International journal of colorectal disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ulrich WirthDepartment of General, Visceral, and Transplant Surgery, Ludwig Maximilian University of Munich, Marchioninistr. 15, D-81377, Munich, Germany. Ulrich.Wirth@med.uni-muenchen.de.ORCID http://orcid.org/0000-0003-2366-8524
Josefine SchardeyDepartment of General, Visceral, and Transplant Surgery, Ludwig Maximilian University of Munich, Marchioninistr. 15, D-81377, Munich, Germany.
Thomas von AhnenDepartment of General, Visceral, Vascular and Endocrine Surgery, Agatharied Hospital, Hausham, Germany.
Petra ZimmermannDepartment of General, Visceral, and Transplant Surgery, Ludwig Maximilian University of Munich, Marchioninistr. 15, D-81377, Munich, Germany.
Florian KühnDepartment of General, Visceral, and Transplant Surgery, Ludwig Maximilian University of Munich, Marchioninistr. 15, D-81377, Munich, Germany.
Jens WernerDepartment of General, Visceral, and Transplant Surgery, Ludwig Maximilian University of Munich, Marchioninistr. 15, D-81377, Munich, Germany.
Hans Martin SchardeyDepartment of General, Visceral, Vascular and Endocrine Surgery, Agatharied Hospital, Hausham, Germany.
Bettina M RauDepartment of Surgery, Kliniken des Landkreises Neumarkt, Neumarkt, Germany.
Julia GumppDepartment of Surgery, Kliniken des Landkreises Neumarkt, Neumarkt, Germany.
Ludwig-Maximilians-Universität München · DEKliniken des Landkreises Lörrach · DEKrankenhaus Agatharied · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is an ongoing debate on whether or not to use oral antibiotic bowel decontamination in colorectal surgery, despite the numerous different regimens in terms of antibiotic substances and duration of application. As we routinely use oral antibiotic bowel decontamination (selective decontamination of the digestive tract (SDD) regimen and SDD regimen plus vancomycin since 2016) in surgery for diverticular disease, our aim was to retrospectively analyze the perioperative outcome in two independent centers.

methodsData from two centers with a routine use of oral antibiotic bowel decontamination for up to 20 years of experience were analyzed for the perioperative outcome of 384 patients undergoing surgery for diverticular disease.

resultsOverall morbidity was 12.8%, overall mortality was 0.3%, the overall rate of anastomotic leakage (AL) was 1.0%, and surgical site infections (SSIs) were 5.5% and 7.8% of all infectious complications including urinary tract infections and pneumonia. No serious adverse events were related to use of oral antibiotic bowel decontamination. Most of the patients (93.8%) completed the perioperative regimen. Additional use of vancomycin to the SDD regimen did not show a further reduction of infectious complications, including SSI and AL.

conclusionOral antibiotic decontamination appears to be safe and effective with low rates of AL and infectious complications in surgery for diverticular disease.

Indexed as

Diverticular DiseasesLaparoscopyAnti-Bacterial AgentsAntibiotic ProphylaxisDecontaminationHumansRetrospective StudiesAnti-Bacterial AgentsAnastomotic leakageDiverticulitisOral antibiotic decontaminationOral antibioticsSDDSigmoid resection

Identifiers

PMID33606074
PMCPMC8279973
OpenAlexW3129776263

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.