Evidence map›Paper›PMID 33605540›Full record

ArticleChemistryOpen2021

A Targeted Nano Drug Delivery System of AS1411 Functionalized Graphene Oxide Based Composites.

Baoqing Liu, Wenzhi Yang, Chengchuan Che, Jinfeng Liu, Meiru Si, Zhijin Gong, Ruixia Gao, Ge Yang

Open access · goldAbstract read
In one paragraph

Article in ChemistryOpen, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Baoqing LiuQufu Normal University, College of Life Sciences, 57 Jingxuan West Road, Qufu City, Shandong, China.
Wenzhi YangInstitution School of Food Science and Nutrition, University of Leeds, Woodhouse Ln, Leeds, LS2 9JT, UK.
Chengchuan CheQufu Normal University, College of Life Sciences, 57 Jingxuan West Road, Qufu City, Shandong, China.
Jinfeng LiuQufu Normal University, College of Life Sciences, 57 Jingxuan West Road, Qufu City, Shandong, China.
Meiru SiQufu Normal University, College of Life Sciences, 57 Jingxuan West Road, Qufu City, Shandong, China.
Zhijin GongQufu Normal University, College of Life Sciences, 57 Jingxuan West Road, Qufu City, Shandong, China.
Ruixia GaoQufu Normal University, College of Life Sciences, 57 Jingxuan West Road, Qufu City, Shandong, China.
Ge YangQufu Normal University, College of Life Sciences, 57 Jingxuan West Road, Qufu City, Shandong, China.ORCID 0000-0002-7023-9143
Qufu Normal University · CNUniversity of Leeds · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel method for the preparation of antitumor drug vehicles has been optimized. Biological materials of chitosan oligosaccharide (CO) and γ-polyglutamic acid (γ-PGA) have previously been employed as modifiers to covalently modify graphene oxide (GO), which in turn loaded doxorubicin (DOX) to obtain a nano drug delivery systems of graphene oxide based composites (GO-CO-γ-PGA-DOX). The system was not equipped with the ability of initiative targeting, thus resulting into toxicity and side effects on normal tissues or organs. In order to further improve the targeting property of the system, the nucleic acid aptamer NH

Indexed as

Antineoplastic AgentsAptamers, NucleotideChitinChitosanDoxorubicinDrug CarriersDrug LiberationGraphiteHeLa CellsHumansImmobilized Nucleic AcidsNanocompositesOligodeoxyribonucleotidesOligosaccharidesPolyglutamic AcidAGRO 100Antineoplastic AgentsAptamers, NucleotideChitinChitosanDoxorubicinDrug Carriersgraphene oxideGraphiteImmobilized Nucleic AcidsoligochitosanOligodeoxyribonucleotidesOligosaccharidespoly(gamma-glutamic acid)Polyglutamic Acidgraphene oxideNH2-AS1411nucleolinTargeted nano drug delivery systems

Identifiers

PMID33605540
PMCPMC8015732
OpenAlexW3130223252

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.