Evidence map›Paper›PMID 33605178›Full record

ArticleDrug delivery2021

Oral delivery of carrier-free dual-drug nanocrystal self-assembled microspheres improved NAD

Hongfei Nie, Yarong Zhang, Haiyang Yu, Hong Xiao, Tao Li, Qian Yang

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. NADMetabolites · 2025
    Article
  8. Review
  9. The Role of NADAmerican journal of cardiovascular drugs : drugs, devices, and other interventions · 2025
    Review
  10. Review
  11. Review
  12. Natural Products from Herbal Medicine Self-Assemble into Advanced Bioactive Materials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  13. NAD in pathological cardiac remodeling: Metabolic regulation and beyond.Biochimica et biophysica acta. Molecular basis of disease · 2024
    Review
  14. Review
  15. Review
  16. Nicotinamide Riboside, a Promising Vitamin BMolecules (Basel, Switzerland) · 2023
    Review
  17. Review
  18. Article
  19. NADJournal of lipid and atherosclerosis · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hongfei NieLaboratory of Mitochondrial and Metabolism, Department of Anesthesiology, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, China.
Yarong ZhangLaboratory of Mitochondrial and Metabolism, Department of Anesthesiology, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, China.
Haiyang YuState Key Laboratory of Oral Disease, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Hong XiaoLaboratory of Mitochondrial and Metabolism, Department of Anesthesiology, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, China.
Tao LiLaboratory of Mitochondrial and Metabolism, Department of Anesthesiology, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, China.
Qian YangLaboratory of Plastic Surgery and Burns, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu, P. R. China.ORCID https://orcid.org/0000-0003-3243-3153
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nicotinamide riboside (NR), as a dietary supplement, can be converted to nicotinamide adenine dinucleotide (NAD

Indexed as

Drug Delivery SystemsAdministration, OralAnimalsBiological AvailabilityDietary SupplementsDisease Models, AnimalDrug LiberationMaleMiceMice, Inbred C57BLMicrospheresNADNanoparticlesNiacinamidePyridinium CompoundsReperfusion InjuryNADNiacinamidenicotinamide-beta-ribosidePyridinium Compoundscardiac I/R injuryCarrier-free microspheresNAD + Bioavailabilitynicotinamide ribosideoral administration

Identifiers

PMID33605178
PMCPMC7899691
OpenAlexW3133485483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.