Evidence map›Paper›PMID 33604944›Full record

ArticleMagnetic resonance in medicine2021

Accelerated radial echo-planar spectroscopic imaging using golden angle view-ordering and compressed-sensing reconstruction with total variation regularization.

Andres Saucedo, Paul M Macey, M Albert Thomas

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andres SaucedoDepartment of Radiological Sciences, University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0002-0277-2966
Paul M MaceySchool of Nursing, University of California, Los Angeles, Los Angeles, California, USA.
M Albert ThomasDepartment of Radiological Sciences, University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0001-9037-2585

Funding

GABA and glutamate changes underlying altered autonomic function in obstructive sleep apneaR01HL135562 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MACEY, PAUL M, THOMAS, MICHAEL ALBERT · 2018 to 2021
$2.9M
Neurochemical Assessment of Sleep Apnea using Accelerated MR Spectroscopic ImagingR56HL131010 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI THOMAS, MICHAEL ALBERT · 2016 to 2016
$648k
Novel Radial Diffusion-Weighted MR Spectroscopic Imaging of HIV: Biomarker Detection Using Functional Imaging and Neurocognitive CorrelatesR21MH125349 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI THOMAS, MICHAEL ALBERT · 2020 to 2021
$413k
NHLBI NIH HHS R01 HL135562NHLBI NIH HHS R56 HL131010NIMH NIH HHS R21 MH125349
6 · The paper itself

Abstract

purposeTo implement a novel, accelerated, 2D radial echo-planar spectroscopic imaging (REPSI) sequence using undersampled radial k-space trajectories and compressed-sensing reconstruction, and to compare results with those from an undersampled Cartesian spectroscopic sequence.

methodsThe REPSI sequence was implemented using golden-angle view-ordering on a 3T MRI scanner. Radial and Cartesian echo-planar spectroscopic imaging (EPSI) data were acquired at six acceleration factors, each with time-equivalent scan durations, and reconstructed using compressed sensing with total variation regularization. Results from prospectively and retrospectively undersampled phantom and in vivo brain data were compared over estimated concentrations and Cramer-Rao lower-bound values, normalized RMS errors of reconstructed metabolite maps, and percent absolute differences between fully sampled and reconstructed spectroscopic images.

resultsThe REPSI method with compressed sensing is able to tolerate greater reductions in scan time compared with EPSI. The reconstruction and quantitation metrics (i.e., spectral normalized RMS error maps, metabolite map normalized RMS error values [e.g., for total N-acetyl asparate, REPSI = 9.4% vs EPSI = 16.3%; acceleration factor = 2.5], percent absolute difference maps, and concentration and Cramer-Rao lower-bound estimates) showed that accelerated REPSI can reduce the scan time by a factor of 2.5 while retaining image and quantitation quality.

conclusionAccelerated MRSI using undersampled radial echo-planar acquisitions provides greater reconstruction accuracy and more reliable quantitation for a range of acceleration factors compared with time-equivalent compressed-sensing reconstructions of undersampled Cartesian EPSI. Compared to the Cartesian approach, radial undersampling with compressed sensing could help reduce 2D spectroscopic imaging acquisition time, and offers a better trade-off between imaging speed and quality.

Indexed as

Echo-Planar ImagingMagnetic Resonance ImagingBrainImage Processing, Computer-AssistedPhantoms, ImagingRetrospective Studiescompressed sensingnonuniform Fourier transformprojection acquisitiontotal variation

Identifiers

PMID33604944
PMCPMC11616894

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.