ArticleAnnals of biomedical engineering2021
Early EEG Alterations Correlate with CTP Hypoperfused Volumes and Neurological Deficit: A Wireless EEG Study in Hyper-Acute Ischemic Stroke.
Article in Annals of biomedical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Quantitative measures of the resting EEG in stroke: a systematic review on clinical correlation and prognostic value.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Pooled it
- Detection of early neurological deterioration using a quantitative electroencephalography system in patients with large vessel occlusion stroke after endovascular treatment.Journal of neurointerventional surgery · 2025Trial
- Binary Classification of Consciousness Using Cerebral Blood Flow and EEG Features.Neurocritical care · 2026Article
- Mapping Brain Function After Stroke: From Early Disorganization to Late Compensation.Neurorehabilitation and neural repair · 2026Article
- Enhancing upper limb motor recovery prediction after acute stroke using EEG and subacute data.APL bioengineering · 2026Article
- Interictal epileptiform activity in the acute stroke phase: an independent predictor of poor outcome.European stroke journal · 2026Article
- Electroencephalography in stroke Care: From acute monitoring to Post-Stroke epilepsy.Clinical neurophysiology practice · 2026Review
- Aperiodic brain activity changes in patients with stroke following virtual reality-based upper limb robotic rehabilitation: a pilot Randomized Controlled Trial.Frontiers in human neuroscience · 2025Article
- Neurological Complications Following Cardiac Surgery: Management and Future Directions.Galen medical journal · 2024Review
- Quantitative EEG as a diagnostic and prognostic tool in hemispheric stroke patients undergoing type A aortic dissection surgery.Brain and behavior · 2023Article
- Cognitive deficit in post-acute COVID-19: an opportunity for EEG evaluation?Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Article
- Cortical connectivity in stroke using signals from resting-state EEG: a review of current literature.Acta neurologica Belgica · 2023Review
- Brain Analysis with a Complex Network Approach in Stroke Patients Based on Electroencephalography: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2023Review
- Stroke-Related Alterations in the Brain's Functional Connectivity Response Associated with Upper Limb Multi-Joint Linkage Movement.Brain sciences · 2023Article
- Clinical Research Progress of the Post-Stroke Upper Limb Motor Function Improvement via Transcutaneous Auricular Vagus Nerve Stimulation.Neural plasticity · 2023Review
- Motor imagery brain-computer interface rehabilitation system enhances upper limb performance and improves brain activity in stroke patients: A clinical study.Frontiers in human neuroscience · 2023Article
- Epileptiform activity in the acute phase of stroke predicts the outcomes in patients without seizures.Frontiers in neurology · 2023Article
- Rapid Response EEG: Current State and Future Directions.Current neurology and neuroscience reports · 2022Review
- The value of mobile magnetic resonance imaging in early warning for stroke: A prospective case-control study.Frontiers in neuroscience · 2022Article
- Value of 4D CT Angiography Combined with Whole Brain CT Perfusion Imaging Feature Analysis under Deep Learning in Imaging Examination of Acute Ischemic Stroke.Computational intelligence and neuroscience · 2022Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain electrical activity in acute ischemic stroke is related to the hypoperfusion of cerebral tissue as manifestation of neurovascular coupling. EEG could be applicable for bedside functional monitoring in emergency settings. We aimed to investigate the relation between hyper-acute ischemic stroke EEG changes, measured with bedside wireless-EEG, and hypoperfused core-penumbra CT-perfusion (CTP) volumes. In addition, we investigated the association of EEG and CTP parameters with neurological deficit measured by NIHSS. We analyzed and processed EEG, CTP and clinical data of 31 anterior acute ischemic stroke patients registered within 4.5 h from symptom onset. Delta/alpha ratio (DAR), (delta + theta)/(alpha + beta) ratio (DTABR) and relative delta power correlated directly (ρ = 0.72; 0.63; 0.65, respectively), while alpha correlated inversely (ρ = - 0.66) with total hypoperfused volume. DAR, DTBAR and relative delta and alpha parameters also correlated with ischemic core volume (ρ = 0.55; 0.50; 0.59; - 0.51, respectively). The same EEG parameters and CTP volumes showed significant relation with NIHSS at admission. The multivariate stepwise regression showed that DAR was the strongest predictor of NIHSS at admission (p < 0.001). The results of this study showed that hyper-acute alterations of EEG parameters are highly related to the extent of hypoperfused tissue highlighting the value of quantitative EEG as a possible complementary tool in the evaluation of stroke severity and its potential role in acute ischemic stroke monitoring.
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