Evidence map›Paper›PMID 33604691›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2021

E-PSMA: the EANM standardized reporting guidelines v1.0 for PSMA-PET.

Francesco Ceci, Daniela E Oprea-Lager, Louise Emmett, Judit A Adam, Jamshed Bomanji, Johannes Czernin, Matthias Eiber, Uwe Haberkorn, Michael S Hofman, Thomas A Hope and 5 more

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 184 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
184citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

184 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. European journal of nuclear medicine and molecular imaging · 2022
    Pooled it
  4. Comparison of [European journal of nuclear medicine and molecular imaging · 2026
    Trial
  5. [European journal of nuclear medicine and molecular imaging · 2026
    Trial
  6. Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Trial
  7. Trial
  8. Patterns of disease detection using [European journal of nuclear medicine and molecular imaging · 2021
    Trial
  9. Article
  10. Review
  11. Automated lesion tracking and treatment response classification on [European journal of nuclear medicine and molecular imaging · 2026
    Article
  12. Review
  13. Stage migration in prostate cancer: the role of PSMA-PET in identifying oligometastatic disease.European journal of nuclear medicine and molecular imaging · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Diagnostic impact of interpretation criteria for [European journal of nuclear medicine and molecular imaging · 2026
    Article
  18. Clinical performance of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  19. Review
  20. Article

124 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Francesco CeciNuclear Medicine, Department of Medical Sciences, University of Turin, Turin, Italy.
Daniela E Oprea-LagerDepartment of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. d.oprea-lager@amsterdamumc.nl.ORCID http://orcid.org/0000-0001-9447-2305
Louise EmmettSt. Vincent's Clinical School, University of New South Wales, Kensington, NSW, Australia.
Judit A AdamDepartment of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Jamshed BomanjiDepartment of Nuclear Medicine, University College London Hospitals NHS Foundation Trust, London, UK.
Johannes CzerninAhmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA.
Matthias EiberSchool of Medicine, Department of Nuclear Medicine, Technische Universität München, Munich, Germany.
Uwe HaberkornDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Michael S HofmanMolecular Imaging and Therapeutic Nuclear Medicine, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Thomas A HopeDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
Rakesh KumarDepartment of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Steven P RoweDivision of Nuclear Medicine, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Sarah M SchwarzenboeckDepartment of Nuclear Medicine, Rostock University Medical Centre, Rostock, Germany.
Stefano FantiNuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Bologna, Italy.
Ken HerrmannDepartment of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium (DKTK), University Hospital Essen, Essen, Germany.

Funding

UCLA SPORE in Brain CancerP50CA211015 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Yvonne Yu-Hsuan Chen · 2017 to 2026
$25.2M
NCI NIH HHS P50 CA211015
6 · The paper itself

Abstract

rationaleThe development of consensus guidelines for interpretation of Prostate-Specific Membrane Antigen (PSMA)-Positron Emission Tomography (PET) is needed to provide more consistent reports in clinical practice. The standardization of PSMA-PET interpretation may also contribute to increasing the data reproducibility within clinical trials. Finally, guidelines in PSMA-PET interpretation are needed to communicate the exact location of findings to referring physicians, to support clinician therapeutic management decisions.

methodsA panel of worldwide experts in PSMA-PET was established. Panelists were selected based on their expertise and publication record in the diagnosis or treatment of PCa, in their involvement in clinical guidelines and according to their expertise in the clinical application of radiolabeled PSMA inhibitors. Panelists were actively involved in all stages of a modified, nonanonymous, Delphi consensus process.

resultsAccording to the findings obtained by modified Delphi consensus process, panelist recommendations were implemented in a structured report for PSMA-PET.

conclusionsThe E-PSMA standardized reporting guidelines, a document supported by the European Association of Nuclear Medicine (EANM), provide consensus statements among a panel of experts in PSMA-PET imaging, to develop a structured report for PSMA-PET in prostate cancer and to harmonize diagnostic interpretation criteria.

Indexed as

Nuclear MedicineProstatic NeoplasmsHumansMalePositron-Emission TomographyPositron Emission Tomography Computed TomographyReproducibility of ResultsConsensus panelEANM guidelinesProstate cancer guidelinesPSMA-PETPSMA prostate cancerStructured report

Identifiers

PMID33604691
PMCPMC8113168

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.