Evidence map›Paper›PMID 33604534›Full record

ArticleWater research X2021

Ozonation products of zidovudine and thymidine in oxidative water treatment.

Jan Funke, Carsten Prasse, Christian Dietrich, Thomas A Ternes

Open access · goldAbstract read
In one paragraph

Article in Water research X, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Remediation strategies of antiretroviral drugs in the aquatic environment: current trend and future perspectives.Water science and technology : a journal of the International Association on Water Pollution Research · 2025
    Review
  3. Article
  4. Review
  5. A critical review on environmental presence of pharmaceutical drugs tested for the covid-19 treatment.Process safety and environmental protection : transactions of the Institution of Chemical Engineers, Part B · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Jan FunkeFederal Institute of Hydrology (BfG), Am Mainzer Tor 1, 56068, Koblenz, Germany.
Carsten PrasseFederal Institute of Hydrology (BfG), Am Mainzer Tor 1, 56068, Koblenz, Germany.
Christian DietrichFederal Institute of Hydrology (BfG), Am Mainzer Tor 1, 56068, Koblenz, Germany.
Thomas A TernesFederal Institute of Hydrology (BfG), Am Mainzer Tor 1, 56068, Koblenz, Germany.
Federal Institute of Hydrology · DEJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ozonation is an advanced treatment technology that is increasingly used for the removal of organic micropollutants from wastewater and drinking water. However, reaction of organic compounds with ozone can also result in the formation of toxic transformation products. In the present study, the degradation of the antiviral drug zidovudine during ozonation was investigated. To obtain further insights into the reaction mechanisms and pathways, results of zidovudine were compared with the transformation of the naturally occurring derivative thymidine. Kinetic experiments were accompanied by elucidation of formed transformation products using lab-scale batch experiments and subsequent liquid chromatography - high resolution mass spectrometry (LC-HRMS) analysis. Degradation rate constants for zidovudine with ozone in the presence of

Indexed as

Antiviral drugsHydroperoxidesOzonationTransformation products

Identifiers

PMID33604534
PMCPMC7873472
OpenAlexW3128991651

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.