ArticleInternational journal of particle therapy2021
Simulation of an HDR "Boost" with Stereotactic Proton versus Photon Therapy in Prostate Cancer: A Dosimetric Feasibility Study.
Article in International journal of particle therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors at 1 institution in 1 country.
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Abstract
PURPOSE/
objectivesTo compare the dose escalation potential of stereotactic body proton therapy (SBPT) versus stereotactic body photon therapy (SBXT) using high-dose rate prostate brachytherapy (HDR-B) dose-prescription metrics. PATIENTS AND
methodsTwenty-five patients previously treated with radiation for prostate cancer were identified and stratified by prostate size (≤ 50cc;
resultsProstate volume receiving 100% of the dose (V100) was significantly greater for SBXT (99%) versus SBPT (96%) (
conclusionSBPT and SBXT can be used to simulate an HDR-B boost for locally advanced prostate cancer. SBPT demonstrated greater dose escalation potential than SBXT. These results are relevant for future trial design, particularly in patients with high risk prostate cancer who are not amenable to brachytherapy.
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