ArticleFrontiers in cell and developmental biology2021
Nicotinamide Mononucleotide Restores the Meiotic Competency of Porcine Oocytes Exposed to Ethylene Glycol Butyl Ether.
Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Physiological premature aging of ovarian blood vessels leads to decline in fertility in middle-aged mice.Nature communications · 2025Article
- Supplementation with NAD+ and its precursors: A rescue of female reproductive diseases.Biochemistry and biophysics reports · 2024Review
- Supplementing Boar Diet with Nicotinamide Mononucleotide Improves Sperm Quality Probably through the Activation of the SIRT3 Signaling Pathway.Antioxidants (Basel, Switzerland) · 2024Article
- Nicotinamide Mononucleotide improves oocyte maturation of mice with type 1 diabetes.Nutrition & diabetes · 2024Article
- Nicotinamide mononucleotide restores oxidative stress-related apoptosis of oocyte exposed to benzyl butyl phthalate in mice.Cell proliferation · 2023Article
- Effects of β-Nicotinamide Mononucleotide, Berberine, and Cordycepin on Lipid Droplet Content and Developmental Ability of Vitrified Bovine Oocytes.Antioxidants (Basel, Switzerland) · 2023Article
- Administration of nicotinamide mononucleotide improves oocyte quality of obese mice.Cell proliferation · 2022Article
- Nicotinamide mononucleotide supplementation improves the quality of porcine oocytes under heat stress.Journal of animal science and biotechnology · 2022Article
- Exposure to Copper Compromises the Maturational Competency of Porcine Oocytes by Impairing Mitochondrial Function.Frontiers in cell and developmental biology · 2021Article
- Pterostilbene Alleviates Chlorpyrifos-Induced Damage During Porcine Oocyte Maturation.Frontiers in cell and developmental biology · 2021Article
- Improvement of oocyte quality through the SIRT signaling pathway.Reproductive medicine and biologyReview
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Authors and funding
8 authors.
Funding
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Abstract
Ethylene glycol butyl ether (EGBE), a type of glycol ethers, is a common chemical used in both industrial and household products. Increasing animal studies have indicated that it produces reproductive problems, such as testicular damage, reduced female fertility, death of embryos, and birth defects. However, how it influences the female germ cells has not yet determined. Here, we found that EGBE exposure resulted in the defective porcine oocyte maturation via disruption of cytoskeleton dynamics, showing the abnormal spindle assembly, chromosome alignment, and actin organization. Meanwhile, EGBE exposure perturbed the mitochondrial distribution and function, leading to the accumulation of reactive oxygen species (ROS) and generation of DNA damage and apoptosis. Of note, nicotinamide mononucleotide (NMN) supplementation rescued the meiotic defects caused by EGBE exposure via restoring NAD
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