Evidence map›Paper›PMID 33604338›Full record

ArticleFrontiers in cell and developmental biology2021

Use of Clodronate Liposomes to Deplete Phagocytic Immune Cells in

Jyothsna Ramesh Kumar, Jessica P Smith, Hyeogsun Kwon, Ryan C Smith

Abstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Distinct roles of theCurrent research in insect science · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Clodronate liposomes untangle the role of hemocytes inbioRxiv : the preprint server for biology · 2025
    Article
  8. International journal of molecular sciences · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Exploring new dimensions of immune cell biology inbioRxiv : the preprint server for biology · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jyothsna Ramesh KumarInterdepartmental Graduate Program in Immunobiology, Iowa State University, Ames, IA, United States.
Jessica P SmithDepartment of Entomology, Iowa State University, Ames, IA, United States.
Hyeogsun KwonDepartment of Entomology, Iowa State University, Ames, IA, United States.
Ryan C SmithDepartment of Entomology, Iowa State University, Ames, IA, United States.

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
The role of hemocytes in mosquito arbovirus infectionR21AI149118 · NIAID · IOWA STATE UNIVERSITY · PI SMITH, RYAN C. · 2020 to 2021
$414k
NIAID NIH HHS R21 AI149118NIH HHS P40 OD018537
6 · The paper itself

Abstract

The innate immune system is the primary defense response to limit invading pathogens for all invertebrate species. In insects, immune cells are central to both cellular and humoral immune responses, however few genetic resources exist beyond

Indexed as

Aedes (Ae.) aegypticlodronate liposomesDrosophila melanogasterhemocytesimmune cellsphagocyte depletionphagocytosis

Identifiers

PMID33604338
PMCPMC7884637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.