ArticleFrontiers in bioengineering and biotechnology2020
A Composite Hydrogel Based on Pectin/Cellulose via Chemical Cross-Linking for Hemorrhage.
Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 45 citations in OpenAlex.
- Design of a Gelatin/Carboxymethyl Cellulose Hydrogel Containing Myrtus Communis Extract with Anti-inflammatory Capabilities for Accelerated Wound Healing; in Vitro and in Vivo Study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2026Article
- Preparation of Hydrogel by Crosslinking and Multi-Dimensional Applications.Gels (Basel, Switzerland) · 2025Review
- Source, Extraction, Properties, and Multifunctional Applications of Pectin: A Short Review.Polymers · 2024Review
- Fabrication and characterization of a novel magnetic nanostructure based on pectin-cellulose hydrogel forRSC advances · 2024Article
- Pectin hydrogels for controlled drug release: Recent developments and future prospects.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024Review
- An architecturally rational hemostat for rapid stopping of massive bleeding on anticoagulation therapy.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Alginate and Chitosan-Based Hydrogel Enhance Antibacterial Agent Activity on Topical Application.Infection and drug resistance · 2024Review
- Pectin Hydrogels: Gel-Forming Behaviors, Mechanisms, and Food Applications.Gels (Basel, Switzerland) · 2023Review
- Hemostasis Strategies and Recent Advances in Nanomaterials for Hemostasis.Molecules (Basel, Switzerland) · 2023Review
- A Comparison of Hemostatic Activities of Zeolite-Based Formulary Finishes on Cotton Dressings.Journal of functional biomaterials · 2023Article
- Tissue engineering modalities in skeletal muscles: focus on angiogenesis and immunomodulation properties.Stem cell research & therapy · 2023Review
- Biophysical Characterization and Cytocompatibility of Cellulose Cryogels Reinforced with Chitin Nanowhiskers.Polymers · 2022Article
- Cellulose Cryogels as Promising Materials for Biomedical Applications.International journal of molecular sciences · 2022Review
- Influence of Carboxymethyl Cellulose on the Stability, Rheological Property, andFrontiers in nutrition · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hydrogel-based material have been demonstrated promising potential for hemostasis. Herein, we prepared a composite hydrogel (CH-P 40%) by combining pectin and cellulose in ionic liquid. The superficial morphology of the CH-P 40% was explored by SEM; the internal chemical bonds, crystal form and thermal stability were determined via FTIR, XRD and thermogravimetric analysis, respectively. The biocompatibilities of the CH-P 40% hydrogel was evaluated by MTT, flow cytometry, and histological observation with H&E staining. Furthermore, the hemostatic effect was evaluated via the blood clotting index and mouse liver hemostatic model. The results showed that the CH-P 40% hydrogel exhibited a dense network structure and retained its chemical bonds, including the OH, CH, C=O, -CH2, CO, C1-H, and β-glycosidic bonds. Simultaneously, the hydrogel retained the Cellulose I and II crystal structure and favorable thermal stability. Moreover, the proliferation rates of CH-P 40%-treated cells increased (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.