Evidence map›Paper›PMID 33604311›Full record

Trial reportResearch and reports in urology2021

Disposable versus Reusable Ureteroscopes: A Prospective Multicenter Randomized Comparison.

Giorgio Bozzini, Beatrice Filippi, Sulieman Alriyalat, Alberto Calori, Umberto Besana, Alexander Mueller, Dmitri Pushkar, Javier Romero-Otero, Antonio Pastore, Maria Chiara Sighinolfi and 3 more

Open access · goldAbstract readCase ReportsClinical Trial
In one paragraph

Trial report in Research and reports in urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Single-useJournal of medicine and life · 2023
    Pooled it
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  12. Editorial Comment.Indian journal of urology : IJU : journal of the Urological Society of India
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 5 countries.

Giorgio BozziniUrology Department, ASST Valle Olona, Busto Arsizio, Varese, Italy.ORCID 0000-0001-6274-314X
Beatrice FilippiUrology Department, Policlinico of Modena, Modena, Italy.ORCID 0000-0002-5556-9304
Sulieman AlriyalatUrology Department, Al-Balqa Applied University, Al-Salt, Jordan.ORCID 0000-0003-3008-0411
Alberto CaloriUrology Department, ASST Valle Olona, Busto Arsizio, Varese, Italy.ORCID 0000-0001-7067-771X
Umberto BesanaUrology Department, ASST Valle Olona, Busto Arsizio, Varese, Italy.
Alexander MuellerDepartment of Urology, University Hospital Zurich, Zurich, Switzerland.
Dmitri PushkarUrology Department First Moscow State Medical University, Moscow, Russia.
Javier Romero-OteroDepartment of Urology, Hospital Universitario 12 de Octubre, Madrid, Spain.
Antonio PastoreUrology Department, Università "La Sapienza", Latina, Italy.ORCID 0000-0003-4293-9174
Maria Chiara SighinolfiUrology Department, Policlinico of Modena, Modena, Italy.
Salvatore MicaliUrology Department, Policlinico of Modena, Modena, Italy.ORCID 0000-0003-2121-1897
Carlo BuizzaUrology Department, ASST Valle Olona, Busto Arsizio, Varese, Italy.
Bernardo RoccoUrology Department, Policlinico of Modena, Modena, Italy.
Azienda Ospedaliero-Universitaria di Modena · ITOspedale di Circolo di Busto Arsizio · ITAl-Balqa Applied University · JOHospital Universitario 12 De Octubre · ESSapienza University of Rome · ITSechenov University · RUUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare reusable and disposable flexible ureteroscopes in terms of efficacy and safety for patients undergoing Retrograde Intrarenal Surgery (RIRS). PATIENTS AND

methodsPatients with a renal stone eligible for RIRS were enrolled in this multicenter, randomized, clinical trial study. Patients were randomized into two groups: group A (90 patients) underwent RIRS with a reusable flexible ureteroscope and group B (90 patients) were treated with a disposable one.

resultsThe patients' demographics, stone features and pre-operative urine cultures were comparable between the groups. The Stone Free Rates (SFRs) were not significantly different (86.6% and 90.0% for group A and group B, respectively, p=0.11) and the mean cost for each procedure was comparable (2321 € in group A vs 2543 € in group B, p=0.09). However, the days of hospitalization and of antibiotic therapy were higher in group A (p ≤ 0.05). The overall complication rate in group A was 8.8% whilst in group B it was 3.3% (p ≤ 0.05); in particular, group A exhibited a greater number of major complications (Clavien score IIIa-V). The overall postoperative infection rate was 16.6% in group A and 3.3% in group B (p ≤ 0.05). Furthermore, none of the patients in group B developed urosepsis or had a positive blood culture, while 3 patients in group A did (p<0.05).

conclusionThe use of disposable ureteroscopes is characterized by significantly lower post-operative complications and infection rates, while having comparable costs and SFRs vis à vis reusable ureteroscopes. Clinical Trial Registration Number: ISRCTN92289221.

Indexed as

disposable ureteroscopeinfectionreusable ureteroscopeRIRS

Identifiers

PMID33604311
PMCPMC7882796
OpenAlexW3126263075

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.