Evidence map›Paper›PMID 33604080›Full record

ArticleImmunometabolism2021

Mitochondrial Calcification.

Bhargavi Duvvuri, Christian Lood

Open access · diamondAbstract read
In one paragraph

Article in Immunometabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Elevated phosphate levels in CKD - a direct threat for the heart.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Review
  6. Review
  7. Calcinosis in dermatomyositis.Current opinion in rheumatology · 2024
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Hierarchy of Bioapatites.International journal of molecular sciences · 2022
    Article
  16. Calcinosis in dermatomyositis: Origins and possible therapeutic avenues.Best practice & research. Clinical rheumatology · 2022
    Review
  17. Mitochondrial Calcium: Effects of Its Imbalance in Disease.Antioxidants (Basel, Switzerland) · 2022
    Review
  18. Review
  19. Oxidative Stress in Optic Neuropathies.Antioxidants (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Bhargavi DuvvuriDepartment of Medicine, Division of Rheumatology, University of Washington, Seattle, WA 98195, USA.
Christian LoodDepartment of Medicine, Division of Rheumatology, University of Washington, Seattle, WA 98195, USA.
University of Washington · US

Funding

Extracellular mitochondria in Inclusion Body MyositisR21AR079542 · NIAMS · UNIVERSITY OF WASHINGTON · PI LOOD, JAN CHRISTIAN · 2021 to 2021
$463k
Mitochondrial calcification in juvenile dermatomyositisR21AR077565 · NIAMS · UNIVERSITY OF WASHINGTON · PI LOOD, JAN CHRISTIAN · 2020 to 2021
$432k
NIAMS NIH HHS R21 AR077565NIAMS NIH HHS R21 AR079542
6 · The paper itself

Abstract

One of the most fascinating aspects of mitochondria is their remarkable ability to accumulate and store large amounts of calcium in the presence of phosphate leading to mitochondrial calcification. In this paper, we briefly address the mechanisms that regulate mitochondrial calcium homeostasis followed by the extensive review on the formation and characterization of intramitochondrial calcium phosphate granules leading to mitochondrial calcification and its relevance to physiological and pathological calcifications of body tissues.

Indexed as

calcificationcalciummitochondriaphosphate

Identifiers

PMID33604080
PMCPMC7889021
OpenAlexW4211010207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.