Evidence map›Paper›PMID 33604040›Full record

ArticleMolecular and clinical oncology2021

Dermatofibrosarcoma protuberans of the breast: A case study.

Dionysios Dimas, Ioannis Boutas, Anastasios Potiris, Nektarios Koufopoulos, Dimitrios Balalis, Kyparissia Sitara, Fotios Danglis, Ioannis Misitzis

Open access · diamondAbstract read
In one paragraph

Article in Molecular and clinical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Dermatofibrosarcoma Protuberans of the Breast.European journal of breast health · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Primary de novo malignant peripheral nerve sheath tumor of the breast mimicking mastitis. Report of a case and review of the literature.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Dionysios DimasBreast Unit, Athens Medical Center, Psychiko Clinic, Athens 11525, Greece.
Ioannis BoutasThird Department of Obstetrics and Gynecology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens 12462, Greece.
Anastasios PotirisThird Department of Obstetrics and Gynecology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens 12462, Greece.
Nektarios KoufopoulosSecond Department of Pathology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens 12462, Greece.
Dimitrios BalalisDepartment of Surgery, Saint Savvas Anti-Cancer Hospital, Athens 11521, Greece.
Kyparissia SitaraBreast Unit, Athens Medical Center, Psychiko Clinic, Athens 11525, Greece.
Fotios DanglisSurgical Pathology Department, National and Kapodistrian University of Athens, Athens 15125, Greece.
Ioannis MisitzisBreast Unit, Athens Medical Center, Psychiko Clinic, Athens 11525, Greece.
National and Kapodistrian University of Athens · GRAthens Medical Center · GRSt Savas Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dermatofibrosarcoma protuberans (DFSP) is a superficial mesenchymal neoplasm that originates from the dermal fibroblasts and tends to be locally aggressive. Although infrequent, it is one of the most common cutaneous sarcomas. It mainly affects young and middle-aged patients 20 to 50 years old. Any area of skin may be involved, but the most common sites of presentation are the trunk and extremities. DFSP of the breast is extremely rare. It classically presents as a nodular, exophytic, cutaneous mass, though initially it can manifest as a flat plague and can show persistent but slow growth for many years. Due to increased risk of local recurrence, the standard of care for localized disease is surgical excision with adequate margins. Wide local excision is the most common technique used, but as an alternative Mohs micrographic surgery has emerged as a procedure that offers lower local recurrence rates. Metastases are rare but have been previously reported. In such patients, treatment with imatinib or radiotherapy can be considered. The current case presents a 52-year-old lady with DFSP of the breast that was successfully managed by the Breast Unit of Athens Medical Center-Psychiko Clinic.

Indexed as

breast lesiondermatofibrosarcoma protuberanssoft tissue tumorsspindle cell tumors

Identifiers

PMID33604040
PMCPMC7849069
OpenAlexW3125198279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.