Evidence map›Paper›PMID 33603996›Full record

ArticleIranian journal of microbiology2020

Evaluation of immunological responses against outer membrane vesicles (OMV) of nontypeable

Ava Behrouzi, Reza Arabi Mianroodi, Parviz Afrough, Ahmad Ayadi, Amirarsalan Serajian

Open access · diamondAbstract read
In one paragraph

Article in Iranian journal of microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ava BehrouziDepartment of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.
Reza Arabi MianroodiDepartment of R&D, Research and Production Complex, Pasteur Institute of Iran, Tehran, Iran.
Parviz AfroughDepartment of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.
Ahmad AyadiDepartment of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.
Amirarsalan SerajianDepartment of Health Education, ACECR, Khuzestan, Ahvaz, Iran.
Pasteur Institute of Iran · IRIslamic Azad University, Ahvaz Branch · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesNontypeable MATERIALS AND

methodsIn this study, standard OMV

resultsThe results showed that total IgG antibody and IgG1 and IgG2a isotypes in OMV immunized mice with mixture of CpG-MPLA adjuvant had a significant increase. Also, the results of cytokines (IL-10, IL-4 and IFN-γ) showed that IL-4 had the highest rate.

conclusionThese findings indicate that OMVs derived from NTHi strains have a high potential to act as a vaccine against NTHi infections.

Indexed as

Non typeable Haemophilus influenzaOuter membrane vesicleVaccine

Identifiers

PMID33603996
PMCPMC7867700
OpenAlexW3105341985

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.