Evidence map›Paper›PMID 33603968›Full record

ArticleACS medicinal chemistry letters2021

Virtual Screening Approach to Identifying a Novel and Tractable Series of

Simon Leiris, David T Davies, Nicolas Sprynski, Jérôme Castandet, Lilha Beyria, Michael S Bodnarchuk, Jonathan M Sutton, Toby M G Mullins, Mark W Jones, Andrew K Forrest and 10 more

Open access · greenAbstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Outsmarting Pathogens with Antibody Engineering.Annual review of chemical and biomolecular engineering · 2023
    Review
  4. Review
  5. Chemical Optimization of SelectiveACS infectious diseases · 2023
    Article
  6. Review
  7. Review
  8. Article
  9. Substrate-Inspired Fragment Merging and Growing Affords Efficacious LasB Inhibitors.Angewandte Chemie (International ed. in English) · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 1 institution in 3 countries.

Simon LeirisAntabio SAS, 436 rue Pierre et Marie Curie, 31670 Labège, France.
David T DaviesAntabio SAS, 436 rue Pierre et Marie Curie, 31670 Labège, France.
Nicolas SprynskiAntabio SAS, 436 rue Pierre et Marie Curie, 31670 Labège, France.
Jérôme CastandetAntabio SAS, 436 rue Pierre et Marie Curie, 31670 Labège, France.
Lilha BeyriaAntabio SAS, 436 rue Pierre et Marie Curie, 31670 Labège, France.
Michael S BodnarchukCharles River Laboratories, Harlow CM19 5TR, U.K.
Jonathan M SuttonCharles River Laboratories, Harlow CM19 5TR, U.K.
Toby M G MullinsCharles River Laboratories, Harlow CM19 5TR, U.K.
Mark W JonesCharles River Laboratories, Harlow CM19 5TR, U.K.
Andrew K ForrestCharles River Laboratories, Harlow CM19 5TR, U.K.
T David PallinCharles River Laboratories, Harlow CM19 5TR, U.K.
Paduri KarunakarGVK Biosciences Private Limited, Plot No. 28 A, IDA Nacharam, Hyderabad 500076, India.
Sathish Kumar MarthaGVK Biosciences Private Limited, Plot No. 28 A, IDA Nacharam, Hyderabad 500076, India.
Battu ParusharamuluGVK Biosciences Private Limited, Plot No. 28 A, IDA Nacharam, Hyderabad 500076, India.
Ramesh RamulaGVK Biosciences Private Limited, Plot No. 28 A, IDA Nacharam, Hyderabad 500076, India.
Venkatesh KothaGVK Biosciences Private Limited, Plot No. 28 A, IDA Nacharam, Hyderabad 500076, India.
Narender PottabathiniGVK Biosciences Private Limited, Plot No. 28 A, IDA Nacharam, Hyderabad 500076, India.
Srinivasu PothukanuriGVK Biosciences Private Limited, Plot No. 28 A, IDA Nacharam, Hyderabad 500076, India.
Marc LemonnierAntabio SAS, 436 rue Pierre et Marie Curie, 31670 Labège, France.
Martin EverettAntabio SAS, 436 rue Pierre et Marie Curie, 31670 Labège, France.
Charles River Laboratories (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel therapies are required to treat chronic bacterial infections in cystic fibrosis (CF) sufferers. The most common pathogen responsible for these infections is

Identifiers

PMID33603968
PMCPMC7883467
OpenAlexW3123196133

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.