Evidence map›Paper›PMID 33603877›Full record

ArticleExperimental and therapeutic medicine2021

Heterogeneity of antigenic constellation in human hepatocellular carcinoma.

Mihai Ceausu, Bogdan Socea, Dragos Serban, Cătălin Gabriel Smarandache, Dragoş Predescu, Nicolae Bacalbaşa, Iulian Slavu, Adrian Tulin, Lucian Alecu, Zenaida Ceauşu

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Measuring HCC Tumor Size in MRI-The Sequence Matters!Diagnostics (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Mihai CeausuDepartment of Pathology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Bogdan SoceaDepartment of Surgery, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Dragos SerbanDepartment of Surgery, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Cătălin Gabriel SmarandacheDepartment of Surgery, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Dragoş PredescuDepartment of Surgery, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Nicolae BacalbaşaDepartment of Obstetrics and Gynecology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Iulian SlavuDepartment of Surgery, 'Prof. Dr. Agrippa Ionescu' Clinical Emergency Hospital, 011356 Bucharest, Romania.
Adrian TulinDepartment of Surgery, 'Prof. Dr. Agrippa Ionescu' Clinical Emergency Hospital, 011356 Bucharest, Romania.
Lucian AlecuDepartment of Surgery, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Zenaida CeauşuPathology Department, 'Sf. Pantelimon' Emergency Hospital, 021659 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROClinical Emergency Hospital Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma is one of the primary liver malignancies responsible for over a million deaths per year worldwide (approximately 10% of all deaths in the adult age range). The diagnosis of HCC can be difficult and often requires the use of more than one microscopic technique. A retrospective study was performed on a study batch of 42 cases that died of HCC due to metastasis or other secondary complications. Tissue samples were taken in order to investigate the tumour antigenic constellation by means of IHC method using a large variety of antibodies.

Indexed as

antigenic mosaicismhepatocellular carcinomahistopathologic variabilityimmunophenotypical heterogeneitymolecular pathology

Identifiers

PMID33603877
PMCPMC7851646
OpenAlexW3126020511

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.