ArticleFrontiers in immunology2020
Magnitude and Kinetics of T Cell and Antibody Responses During H1N1pdm09 Infection in Inbred Babraham Pigs and Outbred Pigs.
Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 31 citations in OpenAlex.
- Genetic and biological characterization of a reassortant H3N2 swine influenza virus isolated in China with internal genes from the 2009 pandemic H1N1.BMC microbiology · 2026Article
- Pathogen-specific immune responses might underlie divergent outcomes of coronavirus and influenza infection in the natural porcine host.Communications biology · 2026Article
- Infectivity of recombinant Torque teno sus virus 1 in pigs coinfected with swine influenza virus.The Journal of general virology · 2026Article
- Postinfection Pig and Ferret Antisera Show Similar Antigenic Profiles for Human Influenza A(H1N1pdm09) Viruses.Influenza and other respiratory viruses · 2026Article
- Efficacy of genetically modified Mycoplasma hyopneumoniae strains and their effect on local and cell-mediated immune responses in pigs.Veterinary research · 2025Article
- Single-cell analysis of pig lung leukocytes and their response to influenza infection and oseltamivir therapy.Journal of immunology (Baltimore, Md. : 1950) · 2025Article
- Epitope-optimized vaccine elicits enduring immunity against swine influenza A virus.Nature communications · 2025Article
- Early disruption of the innate-adaptive immune axisDiscovery immunology · 2025Article
- A genome assembly and transcriptome atlas of the inbred Babraham pig to illuminate porcine immunogenetic variation.Immunogenetics · 2024Article
- An effective vaccine against influenza A virus based on the matrix protein 2 (M2).Veterinary microbiology · 2024Article
- Quantifying the relationship between within-host dynamics and transmission for viral diseases of livestock.Journal of the Royal Society, Interface · 2024Article
- Investigation of activation-induced markers (AIM) in porcine T cells by flow cytometry.Frontiers in veterinary science · 2024Article
- Swine influenza A virus: challenges and novel vaccine strategies.Frontiers in cellular and infection microbiology · 2024Review
- From Snoot to Tail: A Brief Review of Influenza Virus Infection and Immunity in Pigs.Journal of immunology (Baltimore, Md. : 1950) · 2023Review
- Adenoviral-vectored epigraph vaccine elicits robust, durable, and protective immunity against H3 influenza A virus in swine.Frontiers in immunology · 2023Article
- Simultaneous co-infection with swine influenza A and porcine reproductive and respiratory syndrome viruses potentiates adaptive immune responses.Frontiers in immunology · 2023Article
- Effect of mucosal adjuvant IL-1β on heterotypic immunity in a pig influenza model.Frontiers in immunology · 2023Article
- Article
- Spatial, temporal and molecular dynamics of swine influenza virus-specific CD8 tissue resident memory T cells.Mucosal immunology · 2022Article
- Porcine Respiratory Coronavirus as a Model for Acute Respiratory Coronavirus Disease.Frontiers in immunology · 2022Article
Corrections and comments
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Authors and funding
17 authors at 3 institutions in 1 country.
Funding
Abstract
We have used the pig, a large natural host animal for influenza with many physiological similarities to humans, to characterize αβ, γδ T cell and antibody (Ab) immune responses to the 2009 pandemic H1N1 virus infection. We evaluated the kinetic of virus infection and associated response in inbred Babraham pigs with identical MHC (Swine Leucocyte Antigen) and compared them to commercial outbred animals. High level of nasal virus shedding continued up to days 4 to 5 post infection followed by a steep decline and clearance of virus by day 9. Adaptive T cell and Ab responses were detectable from days 5 to 6 post infection reaching a peak at 9 to 14 days. γδ T cells produced cytokines
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.