Evidence map›Paper›PMID 33603726›Full record

ArticleFrontiers in microbiology2021

Mfd Affects Global Transcription and the Physiology of Stressed

Holly Anne Martin, Anitha Sundararajan, Tatiana S Ermi, Robert Heron, Jason Gonzales, Kaiden Lee, Diana Anguiano-Mendez, Faye Schilkey, Mario Pedraza-Reyes, Eduardo A Robleto

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Dynamics of transcription-coupled repair of cyclobutane pyrimidine dimers and (6-4) photoproducts inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. Draft genome ofMicrobiology resource announcements · 2024
    Article
  6. Microbiology and molecular biology reviews : MMBR · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Holly Anne MartinSchool of Life Sciences, University of Nevada, Las Vegas, Las Vegas, NV, United States.
Anitha SundararajanNational Center for Genome Resources, Santa Fe, NM, United States.
Tatiana S ErmiSchool of Life Sciences, University of Nevada, Las Vegas, Las Vegas, NV, United States.
Robert HeronSchool of Life Sciences, University of Nevada, Las Vegas, Las Vegas, NV, United States.
Jason GonzalesWest Career and Technical Academy, Las Vegas, NV, United States.
Kaiden LeeThe College of Idaho, Caldwell, ID, United States.
Diana Anguiano-MendezSchool of Life Sciences, University of Nevada, Las Vegas, Las Vegas, NV, United States.
Faye SchilkeyNational Center for Genome Resources, Santa Fe, NM, United States.
Mario Pedraza-ReyesDivision of Natural and Exact Sciences, Department of Biology, University of Guanajuato, Guanajuato, Mexico.
Eduardo A RobletoSchool of Life Sciences, University of Nevada, Las Vegas, Las Vegas, NV, United States.
University of Nevada, Las Vegas · USNational Center for Genome Resources · USCollege of Idaho · USSoutheast Career Technical Academy · USUniversidad de Guanajuato · MX

Funding

NM-INBRE Sequencing and Bioinformatics CoreP20GM103451 · NIGMS · NEW MEXICO STATE UNIVERSITY LAS CRUCES · PI Charlotte C. Gard · 2012 to 2026
$61.2M
Mfd promotes mutagenesis and prevents protein damage in cells experiencing oxidative stress in Bacillus subtilisR15GM131410 · NIGMS · UNIVERSITY OF NEVADA LAS VEGAS · PI ROBLETO, EDUARDO A · 2018 to 2018
$429k
NIGMS NIH HHS P20 GM103451NIGMS NIH HHS R15 GM131410
6 · The paper itself

Abstract

For several decades, Mfd has been studied as the bacterial transcription-coupled repair factor. However, recent observations indicate that this factor influences cell functions beyond DNA repair. Our lab recently described a role for Mfd in disulfide stress that was independent of its function in nucleotide excision repair and base excision repair. Because reports showed that Mfd influenced transcription of single genes, we investigated the global differences in transcription in wild-type and

Indexed as

Bacillusoxidative stressprotein oxidationstationary-phasetranscription-coupled repair

Identifiers

PMID33603726
PMCPMC7885715
OpenAlexW3125322428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.