ArticlePostepy dermatologii i alergologii2020
Influence of exhaled breath condensates from children with asthma on endothelial cells cultured
Article in Postepy dermatologii i alergologii, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
- Is the composition of exhaled breath condensate a key to explain the course of COVID-19 in children?Postepy dermatologii i alergologii · 2021Article
- Exhaled breath condensates from healthy children induce cell death ofPostepy dermatologii i alergologii · 2021Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
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Abstract
introductionAsthma-associated remodelling involves subepithelial fibrosis and increased vascularization of the bronchial wall. The latter may be associated with excessive production of several angiogenesis regulators which may be found in exhaled breath condensates (EBCs) collected from children with asthma.
aimTo assess the influence of EBC samples of asthmatic children and healthy controls on MATERIAL AND
methodsBreath condensates collected from children with mild asthma (
resultsThe EBCs from patients with asthma revealed a weak inhibitory influence on human and murine endothelial cells. Surprisingly, EBCs from healthy children led to cell death, mainly by the induction of apoptosis. There were no statistically significant differences in the cytokine profile between EBC samples from children with asthma and healthy controls.
conclusionsOur preliminary report shows for the first time that the incubation of EBCs from healthy controls induced apoptosis in endothelial cells. The detailed mechanism responsible for this action remains unknown and requires further research.
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