SynthesisMediators of inflammation2021
The Association of Inflammatory Biomarker of Neutrophil-to-Lymphocyte Ratio with Spontaneous Preterm Delivery: A Systematic Review and Meta-analysis.
Synthesis in Mediators of inflammation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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Who cites it
22 citing papers in PubMed.
- Soluble P2X7 receptor (sP2X7R) as a marker of inflammation in pregnancy.Purinergic signalling · 2026Article
- Among Five First-Trimester Complete Blood Count Inflammatory Indices, the Systemic Inflammation Response Index Rises Most Consistently with the Severity of Preterm Birth.Diagnostics (Basel, Switzerland) · 2026Article
- Article
- Immunological maladaptation preceding spontaneous preterm birth in human pregnancies.Nature communications · 2026Article
- Neutrophil-to-lymphocyte ratio at admission helps to predict the need for blood transfusion after vaginal delivery.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- The neutrophil-to-lymphocyte ratio: a marker for microbial invasion of the amniotic cavity in preterm prelabor rupture of membranes.Obstetrics & gynecology science · 2026Article
- The association of inflammatory markers with cerclage failure in twin pregnancies.BMC pregnancy and childbirth · 2026Article
- Association of immunonutrition-based indices (Hemoglobin-Albumin-Lymphocyte-Platelet, prognostic nutritional index, and C-reactive protein-albumin-lymphocyte) with the latency period in preterm prelabor rupture of membranes.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Predictive Value of Neutrophils, Lymphocytes, Platelets, Neutrophil-Lymphocyte Ratio (NLR), and Platelets-Lymphocyte Ratio (PLR) in Preterm Labor: Single and Combined Indices.Obstetrics and gynecology international · 2026Article
- Endometrial immune cell profile at the time of frozen embryo transfer as prognostic indicator of live birth.Frontiers in immunology · 2026Observational
- Neutrophil-To-Lymphocyte Ratio and Delivery Within 24 h in Preterm Premature Rupture of Membranes: A Retrospective Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- The Association Between Longer Maternal Leukocyte Telomere Length in the Immediate Postpartum Period and Preterm Birth in a Predominately Latina Cohort of Mothers.Maternal and child health journal · 2025Article
- The single-cell immune profile throughout gestation and its potential value for identifying women at risk for spontaneous preterm birth.European journal of obstetrics & gynecology and reproductive biology: X · 2025Review
- Impact of the adenosine receptor A2BR expressed on myeloid cells on immune regulation during pregnancy.European journal of immunology · 2024Article
- Predicting Spontaneous Preterm Birth Using the Immunome.Clinics in perinatology · 2024Review
- Longitudinal Cervical Length Measurements and Spontaneous Preterm Birth in Singleton and Twin Pregnancies.JAMA network open · 2024Article
- Can the neutrophil-to-lymphocyte ratio be used as an early marker of small fetuses for gestational age? A prospective study.Frontiers in medicine · 2024Article
- Neutrophil-to-Lymphocyte Ratio (NLR) and Platelet-to-Lymphocyte Ratio (PLR) Can Predict Spontaneous Preterm Birth?Journal of inflammation research · 2023Article
- The Predictive Role of Maternal Biological Markers and Inflammatory Scores NLR, PLR, MLR, SII, and SIRI for the Risk of Preterm Delivery.Journal of clinical medicine · 2022Article
- The Role of Neutrophils in Pregnancy, Term and Preterm Labour.Life (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeutrophil-to-lymphocyte ratio (NLR), as an inflammatory biomarker, has been investigated in several studies for early prediction of preterm delivery. However, their findings seem to be controversial. Thus, this systematic review and meta-analysis was conducted to evaluate the role of NLR in predicting preterm delivery as compared to term controls.
methodsPubMed, Web of Science, Embase, Scopus, and Google Scholar were systematically searched from inception up to December 2020. Interstudy heterogeneity was assessed using Cochrane's
resultsOut of a total of 4369 recodes, fifteen articles including 3327 participants were enrolled. The meta-analysis finding using the random-effects model produced a pooled estimate suggesting a significantly higher NLR (WMD = 1.23, 95% CI: 0.40-2.07) in women with preterm delivery (
conclusionThe results of this meta-analysis revealed that the NLR value is higher in patients with preterm delivery. The NLR could be a useful biomarker for predicting preterm delivery; however, further prospective case-control studies are required to produce stronger evidence.
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