ArticleHIV/AIDS (Auckland, N.Z.)2021
Retention in Care and Health Outcomes of HIV-Exposed Infants in a Prevention of Mother-to-Child Transmission of HIV (PMTCT) Cohort in Addis Ababa, Ethiopia.
Article in HIV/AIDS (Auckland, N.Z.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Magnitude and risk factors of mother-to-child transmission of HIV among HIV-exposed infants after Option B+ implementation in Ethiopia: a systematic review and meta-analysis.AIDS research and therapy · 2024Pooled it
- Article
- A qualitative study on reasons for women's loss and resumption of Option B plus care in Ethiopia.Scientific reports · 2024Article
- Optimization of the vertical transmission prevention program in Guinea: impact of the improvement plan on performance indicators at large-cohort sites.AIDS research and therapy · 2024Review
- Prevention of mother-to-child transmission of HIV service interruptions amid COVID-19 pandemic.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2024Article
- Attrition from care and its predictors among women exposed to dolutegravir- and efavirenz-based first-line antiretroviral therapy in Ethiopia: a before-and-after study.Frontiers in public health · 2024Article
- Effect of Dolutegravir-Based First-Line Antiretroviral Therapy on Mother-to-Child Transmission of HIV Among HIV-Exposed Infants in Ethiopia: a Before-and-After Study.HIV/AIDS (Auckland, N.Z.) · 2024Article
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCurrently, a high number of mother-infant cohorts do not complete the full cascade of prevention of mother-to-child transmission of HIV (PMTCT) services in Ethiopia. This study examined the level of HIV-exposed infants discharged negative and rate of loss to follow-up (LTFU) in a mother-infant cohort in Addis Ababa, Ethiopia.
methodsA retrospective cohort study was conducted in selected public health facilities of Addis Ababa. Data were abstracted from infant and mother registration cards and mother-infant cohort follow-up charts. The proportion of HIV-exposed infants discharged negative was examined. LTFU was then analyzed and a Kaplan-Meier survival curve was used to estimate Cumulative probability of LTFU among the different groups. Cox proportional hazard model was used to determine significant factors associated with LTFU.
resultsThree hundred fifty six mother-infant pairs were included in this study. The LTFU rate at the end of follow-up period was of 13.2% (95% CI= 9.83-17.6%) and an overall HIV transmission rate of 0.61% was observed. Younger women (AHR=0.90, 95% CI = 0.83-0.97) and those who were newly diagnosed at the time of entry to PMTCT (AHR=0.35, 95% CI = 0.18-0.68) were less likely to complete PMTCT.
conclusionHigh retention to PMTCT services and low mother-to-child HIV transmission rate was observed. To successfully achieve the PMTCT program outcomes, more emphasis should be given to younger women and to those newly enrolled in the PMTCT program.
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