ArticleScientific reports2021
The association between dietary fatty acid intake and the risk of developing preeclampsia: a matched case-control study.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Nutrient intakes of pregnant and lactating women in Indonesia and Malaysia: Systematic review and meta-analysis.Frontiers in nutrition · 2023Pooled it
- Association of the maternal fish and PUFA intake with the risk of hypertensive disorders of pregnancy: a nationwide birth cohort-The Japan Environment and Children's Study (JECS).European journal of nutrition · 2026Article
- Article
- Plasma fatty acid associated with risk of gastrointestinal cancer: a prospective cohort study from UK Biobank.Translational cancer research · 2026Article
- The Role of Docosahexaenoic Acid in the Development of Preeclampsia and Perinatal Outcomes.Diagnostics (Basel, Switzerland) · 2026Article
- Multidimensional Plasma Lipids Affect Preeclampsia/Eclampsia: A Mendelian Randomization Study.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA)-Should They Be Mandatory Supplements in Pregnancy?Biomedicines · 2024Review
- Paradoxes: Cholesterol and Hypoxia in Preeclampsia.Biomolecules · 2024Review
- DHA supplementation and pregnancy complications.Journal of translational medicine · 2023Review
- Lifestyle and the hypertensive disorders of pregnancy in nulliparous women in the United States: a secondary data analysis of the nuMom2b.BMC pregnancy and childbirth · 2023Article
- Dietary carotenoid intake and risk of developing preeclampsia: a hospital-based case-control study.BMC pregnancy and childbirth · 2022Article
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Authors and funding
13 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The association between dietary fat intake during pregnancy and the risk of developing preeclampsia has been examined in many epidemiological studies, but the results remain inconsistent. The aim of this study was to clarify this association in pregnant Chinese women. After conducting 1:1 matching, 440 pairs consisting of pregnant women with preeclampsia and hospital-based, healthy pregnant women matched by gestational week (± 1 week) and age (± 3 years) were recruited. A 79-item semi-quantitative food frequency questionnaire administered during face-to-face interviews was used to estimate the participants' dietary intake of fatty acids. We found that the intakes of arachidonic acid (AA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) were inversely associated with the risk of developing preeclampsia. Compared with the lowest quartile intake, the multivariate-adjusted odds ratios (95% confidence interval) of the highest quartile intake were 0.42 (0.26-0.68, p-trend < 0.001) for EPA, 0.52 (0.3-0.83, p-trend = 0.005) for DHA, and 0.41 (0.19-0.88, p-trend = 0.007) for AA. However, we did not observe any significant associations between the intake of total fatty acids, saturated fatty acids, and mono-unsaturated fatty acids and the risk of developing preeclampsia. Our results showed that the dietary intake of long-chain polyunsaturated fatty acids (i.e., EPA, DHA, and AA) may protect pregnant Chinese women against the development of preeclampsia.
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