Evidence map›Paper›PMID 33602952›Full record

ArticleScientific reports2021

Isolation and characterization of chitosan from Ugandan edible mushrooms, Nile perch scales and banana weevils for biomedical applications.

Kenneth Ssekatawa, Denis K Byarugaba, Eddie M Wampande, Tlou N Moja, Edward Nxumalo, Malik Maaza, Juliet Sackey, Francis Ejobi, John Baptist Kirabira

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 81 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Kenneth SsekatawaCollege of Veterinary Medicine Animal Resources and Biosecurity, Makerere University, P. O. Box 7062, Kampala, Uganda.
Denis K ByarugabaCollege of Veterinary Medicine Animal Resources and Biosecurity, Makerere University, P. O. Box 7062, Kampala, Uganda.
Eddie M WampandeCollege of Veterinary Medicine Animal Resources and Biosecurity, Makerere University, P. O. Box 7062, Kampala, Uganda.
Tlou N MojaUniversity of South Africa-Florida, Campus Private Bag X6, Florida, 1710, South Africa.
Edward NxumaloUniversity of South Africa-Florida, Campus Private Bag X6, Florida, 1710, South Africa.
Malik MaazaNanosciences African Network (NANOAFNET), iThemba LABS-National Research Foundation, Old Faure Road, Somerset West, 7129, South Africa.
Juliet SackeyNanosciences African Network (NANOAFNET), iThemba LABS-National Research Foundation, Old Faure Road, Somerset West, 7129, South Africa.
Francis EjobiCollege of Veterinary Medicine Animal Resources and Biosecurity, Makerere University, P. O. Box 7062, Kampala, Uganda.
John Baptist KirabiraAfrican Center of Excellence in Materials, Product Development and Nanotechnology, College of Engineering, Design, Art and Technology, Makerere University, P. O. Box 7062, Kampala, Uganda. kirabirajb@gmail.com.
Makerere University · UGUniversity of South Africa · ZANational Research Foundation · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Of recent, immense attention has been given to chitosan in the biomedical field due to its valuable biochemical and physiological properties. Traditionally, the chief source of chitosan is chitin from crab and shrimp shells. Chitin is also an important component of fish scales, insects and fungal cell walls. Thus, the aim of this study was to isolate and characterize chitosan from locally available material for potential use in the biomedical field. Chitosan ash and nitrogen contents ranged from 1.55 to 3.5% and 6.6 to 7.0% respectively. Molecular weight varied from 291 to 348KDa. FTIR spectra revealed high degree of similarity between locally isolated chitosan and commercial chitosan with DD ranging from 77.8 to 79.1%. XRD patterns exhibited peaks at 2θ values of 19.5° for both mushroom and banana weevil chitosan while Nile perch scales chitosan registered 3 peaks at 2θ angles of 12.3°, 20.1° and 21.3° comparable to the established commercial chitosan XRD pattern. Locally isolated chitosan exhibited antimicrobial activity at a very high concentration. Ash content, moisture content, DD, FTIR spectra and XRD patterns revealed that chitosan isolated from locally available materials has physiochemical properties comparable to conventional chitosan and therefore it can be used in the biomedical field.

Indexed as

AgaricalesAnimalsAnimal ShellsBrachyuraChitinChitosanMolecular WeightMusaPerchesSpectroscopy, Fourier Transform InfraredUgandaWeevilsX-Ray DiffractionChitinChitosan

Identifiers

PMID33602952
PMCPMC7892825
OpenAlexW3114475042

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.