Evidence map›Paper›PMID 33602941›Full record

ArticleNature communications2021

Histamine H

Li Cheng, Cenglin Xu, Lu Wang, Dadao An, Lei Jiang, Yanrong Zheng, Yixin Xu, Yi Wang, Yujing Wang, Kuo Zhang and 9 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. Article
  6. Article
  7. Histamine HNeuroscience bulletin · 2025
    Article
  8. Histamine HNature communications · 2024
    Article
  9. Targeting the Central Histamine HNeuroscience bulletin · 2024
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Histamine HProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Nicotine rebalances NADNature communications · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 2 countries.

Li Cheng *Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Cenglin Xu *Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.ORCID 0000-0002-4337-3777
Lu Wang *Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Dadao AnInstitute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Lei JiangInstitute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Yanrong ZhengInstitute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Yixin XuInstitute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Yi WangInstitute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.ORCID 0000-0002-1350-2961
Yujing WangInstitute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Kuo ZhangDepartment of Pharmacology, Shenyang Pharmaceutical University, Shenyang, P.R. China.
Xiaodong WangInstitute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.ORCID 0000-0001-7730-3710
Xiangnan ZhangInstitute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.ORCID 0000-0002-7603-7403
Aimin BaoInstitute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Yudong ZhouInstitute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.ORCID 0000-0002-6364-3869
Jingyu YangDepartment of Pharmacology, Shenyang Pharmaceutical University, Shenyang, P.R. China.
Shumin DuanInstitute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.ORCID 0000-0002-0466-1821
Dick F SwaabNetherlands Institute for Neuroscience, an Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, BA, the Netherlands.
Weiwei HuInstitute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China. huww@zju.edu.cn.ORCID 0000-0002-7768-6907
Zhong ChenInstitute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China. chenzhong@zju.edu.cn.ORCID 0000-0003-4755-9357
Zhejiang University · CNZhejiang Chinese Medical University · CNShenyang Pharmaceutical University · CNNetherlands Institute for Neuroscience · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Negative symptoms in schizophrenia strongly contribute to poor functional outcomes, however its pathogenesis is still unclear. Here, we found that histamine H

Indexed as

Sensory GatingSocial BehaviorAnhedoniaAnimalsBehavior, AnimalCholine O-AcetyltransferaseCholinergic NeuronsCognitive DysfunctionDizocilpine MaleateFemaleIntegrasesLocomotionMaleMiceMice, TransgenicPrefrontal CortexCholine O-AcetyltransferaseCre recombinaseDizocilpine MaleateIntegrasesReceptors, Histamine H1

Identifiers

PMID33602941
PMCPMC7893046
OpenAlexW3132728711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.