ArticleNature communications2021
Acoustofluidic rotational tweezing enables high-speed contactless morphological phenotyping of zebrafish larvae.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
47 citing papers in PubMed.
- On-demand rotational manipulation of microparticles and zebrafish larvae via orthogonally phased BAW acoustofluidics.Microsystems & nanoengineering · 2026Article
- Dielectrophoretic and acoustophoretic dual-sensing electroluminescent display.Nature communications · 2026Article
- Integrated microfluidic biosensors: shaping the future of quantitative life sciences and on-chip molecular diagnostics.Lab on a chip · 2026Review
- Helical opto-thermoviscous flows drive out-of-plane rotation and particle spinning in a highly viscous micro-environment.Light, science & applications · 2026Article
- Surface Acoustic Wave Devices: New Mechanisms, Enabling Techniques, and Application Frontiers.Micromachines · 2026Review
- Steering mass transport with topologically protected sound.National science review · 2026Article
- Demonstration of topological acoustic tweezing for robust mass transport.Science advances · 2026Article
- On-chip phased interdigital metamaterials enable versatile manipulation of surface acoustic waves, microfluids, and micro/nano-objects.Nature communications · 2025Article
- iCAT as an open-source platform for axial rotation and high-resolution imaging of organoids and living organisms.Communications biology · 2025Article
- Enhancing Microparticle Separation Efficiency in Acoustofluidic Chips via Machine Learning and Numerical Modeling.Sensors (Basel, Switzerland) · 2025Article
- In-Petri-Dish Traveling and Standing Acoustic Wave-Assisted Fabrication of Anisotropic Collagen Hydrogels.Materials advances · 2025Article
- End-to-end inverse design for programmable acoustic tweezers with simultaneous force and torque control by metasurfaces.Science advances · 2025Article
- Zebrafish as a vertebrate model for high-throughput drug toxicity screening: Mechanisms, novel techniques, and future perspectives.Journal of pharmaceutical analysis · 2025Review
- Acoustic Tweezers for Microscopy of Living Organisms.IEEE transactions on bio-medical engineering · 2025Article
- Acoustofluidic spin control for 3D particle manipulation in droplets.Science advances · 2025Article
- Streaming-based Tweezers for Routing, Engineering, and Manipulation of multiparticles: STREAM.Microsystems & nanoengineering · 2025Article
- Fully automated in vivo screening system for multi-organ imaging and pharmaceutical evaluation.Microsystems & nanoengineering · 2025Article
- Wireless Frequency-Multiplexed Acoustic Array-based Acoustofluidics.Advanced materials technologies · 2024Article
- Acoustic Waves Coupling with Polydimethylsiloxane in Reconfigurable Acoustofluidic Platform.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Sound innovations for biofabrication and tissue engineering.Microsystems & nanoengineering · 2024Review
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
Modern biomedical research and preclinical pharmaceutical development rely heavily on the phenotyping of small vertebrate models for various diseases prior to human testing. In this article, we demonstrate an acoustofluidic rotational tweezing platform that enables contactless, high-speed, 3D multispectral imaging and digital reconstruction of zebrafish larvae for quantitative phenotypic analysis. The acoustic-induced polarized vortex streaming achieves contactless and rapid (~1 s/rotation) rotation of zebrafish larvae. This enables multispectral imaging of the zebrafish body and internal organs from different viewing perspectives. Moreover, we develop a 3D reconstruction pipeline that yields accurate 3D models based on the multi-view images for quantitative evaluation of basic morphological characteristics and advanced combinations of metrics. With its contactless nature and advantages in speed and automation, our acoustofluidic rotational tweezing system has the potential to be a valuable asset in numerous fields, especially for developmental biology, small molecule screening in biochemistry, and pre-clinical drug development in pharmacology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.