Evidence map›Paper›PMID 33602909›Full record

ArticleNature communications2021

Genome-wide association studies provide insights into the genetic determination of fruit traits of pear.

Ming-Yue Zhang, Cheng Xue, Hongju Hu, Jiaming Li, Yongsong Xue, Runze Wang, Jing Fan, Cheng Zou, Shutian Tao, Mengfan Qin and 11 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
27.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 118 citations in OpenAlex.

  1. Article
  2. Article
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  4. The transcription factor AebHLH89 activatesHorticulture research · 2026
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  5. 3D Chromatin Architecture Provides Insights Into Leaf Trait Variation Among Pear Species.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  6. Article
  7. Whole-genome resequencing of 495Horticulture research · 2026
    Article
  8. Article
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  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Nitrate Modulates Fruit Lignification by RegulatingInternational journal of molecular sciences · 2025
    Article
  18. Article
  19. Plant phenomics (Washington, D.C.) · 2025
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 2 countries.

Ming-Yue Zhang *Centre of Pear Engineering Technology Research, State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Cheng Xue *Centre of Pear Engineering Technology Research, State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, Jiangsu, China.ORCID http://orcid.org/0000-0002-3541-9958
Hongju Hu *Wuchang Sand Pear Germplasm, Hubei Academy of Agricultural Sciences, Wuhan, Hubei, China.
Jiaming Li *Centre of Pear Engineering Technology Research, State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Yongsong Xue *Centre of Pear Engineering Technology Research, State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Runze WangCentre of Pear Engineering Technology Research, State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Jing FanWuchang Sand Pear Germplasm, Hubei Academy of Agricultural Sciences, Wuhan, Hubei, China.
Cheng ZouInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Shutian TaoCentre of Pear Engineering Technology Research, State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Mengfan QinCentre of Pear Engineering Technology Research, State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Bing BaiCentre of Pear Engineering Technology Research, State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Xiaolong LiCentre of Pear Engineering Technology Research, State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Chao GuCentre of Pear Engineering Technology Research, State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Shan WuBoyce Thompson Institute, Cornell University, Ithaca, NY, USA.ORCID http://orcid.org/0000-0001-8539-3808
Xu ChenHaixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, China.
Guangyan YangCentre of Pear Engineering Technology Research, State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Yueyuan LiuCentre of Pear Engineering Technology Research, State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Manyi SunCentre of Pear Engineering Technology Research, State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Zhangjun FeiBoyce Thompson Institute, Cornell University, Ithaca, NY, USA. zf25@cornell.edu.ORCID http://orcid.org/0000-0001-9684-1450
Shaoling ZhangCentre of Pear Engineering Technology Research, State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, Jiangsu, China. slzhang@njau.edu.cn.
Jun WuCentre of Pear Engineering Technology Research, State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, Jiangsu, China. wujun@njau.edu.cn.ORCID http://orcid.org/0000-0002-1566-5115
Nanjing Agricultural University · CNCornell University · USHubei Academy of Agricultural Sciences · CNChinese Academy of Agricultural Sciences · CNFujian Agriculture and Forestry University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pear is a major fruit tree crop distributed worldwide, yet its breeding is a very time-consuming process. To facilitate molecular breeding and gene identification, here we have performed genome-wide association studies (GWAS) on eleven fruit traits. We identify 37 loci associated with eight fruit quality traits and five loci associated with three fruit phenological traits. Scans for selective sweeps indicate that traits including fruit stone cell content, organic acid and sugar contents might have been under continuous selection during breeding improvement. One candidate gene, PbrSTONE, identified in GWAS, has been functionally verified to be involved in the regulation of stone cell formation, one of the most important fruit quality traits in pear. Our study provides insights into the complex fruit related biology and identifies genes controlling important traits in pear through GWAS, which extends the genetic resources and basis for facilitating molecular breeding in perennial trees.

Indexed as

Genome-Wide Association StudyArabidopsisFruitGenes, PlantGenetics, PopulationGenetic VariationLigninPhylogenyPlants, Genetically ModifiedPyrusQuantitative Trait LociReproducibility of ResultsLignin

Identifiers

PMID33602909
PMCPMC7892570
OpenAlexW3133228620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.