Evidence map›Paper›PMID 33602861›Full record

ArticleThe European respiratory journal2021

Single-cell RNA sequencing identifies macrophage transcriptional heterogeneities in granulomatous diseases.

Shu-Yi Liao, Shaikh M Atif, Kara Mould, Iain R Konigsberg, Rui Fu, Elizabeth Davidson, Li Li, Andrew P Fontenot, Lisa A Maier, Ivana V Yang

Open access · bronzeAbstract readLetter
In one paragraph

Article in The European respiratory journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Cardiovascular Manifestations and Immunobiology of Sarcoidosis.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  2. Article
  3. Overview of multi-omics approaches for pulmonary sarcoidosis.EC pulmonology and respiratory medicine · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Immune mechanisms in fibrotic pulmonary sarcoidosis.European respiratory review : an official journal of the European Respiratory Society · 2022
    Review
  9. Article
  10. Innate and Adaptive Immunity in Noninfectious Granulomatous Lung Disease.Journal of immunology (Baltimore, Md. : 1950) · 2022
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Shu-Yi LiaoDept of Medicine, National Jewish Health, Denver, CO, USA.
Shaikh M AtifDept of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Kara MouldDept of Medicine, National Jewish Health, Denver, CO, USA.
Iain R KonigsbergDept of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Rui FuRNA Biosciences Initiative, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Elizabeth DavidsonDept of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Li LiDept of Medicine, National Jewish Health, Denver, CO, USA.
Andrew P FontenotDept of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Lisa A MaierDept of Medicine, National Jewish Health, Denver, CO, USA.
Ivana V YangDept of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA Ivana.Yang@CUAnschutz.edu.
University of Colorado Anschutz Medical Campus · USNational Jewish Health · USUniversity of Colorado Denver · USColorado School of Public Health · US

Funding

T cell epitopes in sarcoidosisR01HL136137 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI PALMER, BRENT E · 2017 to 2024
$4.7M
Predictive Models of Beryllium Sensitization and Chronic Beryllium DiseaseR01ES034767 · NIEHS · NATIONAL JEWISH HEALTH · PI Maneesh Bhargava, Li Li · 2023 to 2026
$3.2M
Epigenetic Regulation of Immune Pathways in SarcoidosisR01HL140357 · NHLBI · NATIONAL JEWISH HEALTH · PI MAIER, LISA A, YANG, IVANA V · 2018 to 2021
$2.8M
Role of Chemokines in Innate and Adaptive Immunity in the LungR01HL152756 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ATIF, SHAIKH M · 2020 to 2023
$2.4M
Exposure in Epigenetic Regulation of Immune Response in CBDR01ES023826 · NIEHS · NATIONAL JEWISH HEALTH · PI MAIER, LISA A, YANG, IVANA V · 2015 to 2019
$2.3M
Interactions between antigen-specific effector and regulatory T cells in beryllium-induced diseaseR01ES025534 · NIEHS · UNIVERSITY OF COLORADO DENVER · PI FONTENOT, ANDREW P. · 2016 to 2020
$2.1M
The immunoregulatory role of Alveolar Macrophages in Chronic Beryllium DiseaseR01ES025722 · NIEHS · NATIONAL JEWISH HEALTH · PI LI, LI · 2016 to 2020
$1.8M
Patient-Oriented Research in Immunologic Lung Disease.K24HL102245 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI FONTENOT, ANDREW P. · 2010 to 2020
$1.4M
Metabolic Reprogramming of Recruited Alveolar Macrophages by Arginine In Acute Lung InjuryK08HL141648 · NHLBI · NATIONAL JEWISH HEALTH · PI MOULD, KARA J · 2018 to 2022
$798k
NHLBI NIH HHS K08 HL141648NHLBI NIH HHS K24 HL102245NHLBI NIH HHS R01 HL136137NHLBI NIH HHS R01 HL140357NHLBI NIH HHS R01 HL152756NIEHS NIH HHS R01 ES023826NIEHS NIH HHS R01 ES025534NIEHS NIH HHS R01 ES025722NIEHS NIH HHS R01 ES034767
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

GranulomaMacrophagesHumansSequence Analysis, RNA

Identifiers

PMID33602861
PMCPMC8247459
OpenAlexW3129323773

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.