Evidence map›Paper›PMID 33602822›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

The male germline-specific protein MAPS is indispensable for pachynema progression and fertility.

Miao Li, Jiahuan Zheng, Gaopeng Li, Zexiong Lin, Dongliang Li, Dongteng Liu, Haiwei Feng, Dandan Cao, Ernest H Y Ng, Raymond H W Li and 5 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

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  7. Sex body: A nest of protein mixture.Frontiers in cell and developmental biology · 2023
    Review
  8. Article
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  11. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 3 countries.

Miao LiShenzhen Key Laboratory of Fertility Regulation, Center of Assisted Reproduction and Embryology, The University of Hong Kong-Shenzhen Hospital, 518053 Shenzhen, Guangdong, China.ORCID 0000-0002-1914-3955
Jiahuan ZhengShenzhen Key Laboratory of Fertility Regulation, Center of Assisted Reproduction and Embryology, The University of Hong Kong-Shenzhen Hospital, 518053 Shenzhen, Guangdong, China.
Gaopeng LiDepartment of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294-0024.ORCID 0000-0003-1148-7267
Zexiong LinShenzhen Key Laboratory of Fertility Regulation, Center of Assisted Reproduction and Embryology, The University of Hong Kong-Shenzhen Hospital, 518053 Shenzhen, Guangdong, China.
Dongliang LiShenzhen Key Laboratory of Fertility Regulation, Center of Assisted Reproduction and Embryology, The University of Hong Kong-Shenzhen Hospital, 518053 Shenzhen, Guangdong, China.
Dongteng LiuShenzhen Key Laboratory of Fertility Regulation, Center of Assisted Reproduction and Embryology, The University of Hong Kong-Shenzhen Hospital, 518053 Shenzhen, Guangdong, China.
Haiwei FengShenzhen Key Laboratory of Fertility Regulation, Center of Assisted Reproduction and Embryology, The University of Hong Kong-Shenzhen Hospital, 518053 Shenzhen, Guangdong, China.
Dandan CaoShenzhen Key Laboratory of Fertility Regulation, Center of Assisted Reproduction and Embryology, The University of Hong Kong-Shenzhen Hospital, 518053 Shenzhen, Guangdong, China.ORCID 0000-0003-2899-8813
Ernest H Y NgShenzhen Key Laboratory of Fertility Regulation, Center of Assisted Reproduction and Embryology, The University of Hong Kong-Shenzhen Hospital, 518053 Shenzhen, Guangdong, China.
Raymond H W LiShenzhen Key Laboratory of Fertility Regulation, Center of Assisted Reproduction and Embryology, The University of Hong Kong-Shenzhen Hospital, 518053 Shenzhen, Guangdong, China.
Chunsheng HanState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, 100101 Beijing, China.
William S B YeungShenzhen Key Laboratory of Fertility Regulation, Center of Assisted Reproduction and Embryology, The University of Hong Kong-Shenzhen Hospital, 518053 Shenzhen, Guangdong, China.ORCID 0000-0003-0670-0879
Louise T ChowDepartment of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294-0024; ltchow@uab.edu hbwang@uab.edu kliugc@hku.hk.
Hengbin WangDepartment of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294-0024; ltchow@uab.edu hbwang@uab.edu kliugc@hku.hk.ORCID 0000-0003-2414-0609
Kui LiuShenzhen Key Laboratory of Fertility Regulation, Center of Assisted Reproduction and Embryology, The University of Hong Kong-Shenzhen Hospital, 518053 Shenzhen, Guangdong, China; ltchow@uab.edu hbwang@uab.edu kliugc@hku.hk.ORCID 0000-0002-7519-3332
Chinese University of Hong Kong · HKUniversity of Alabama at Birmingham · USUniversity of Hong Kong - Shenzhen Hospital · CNChinese Academy of Sciences · CN

Funding

Remodeling and Spacing Factor 1 in Histone H2A Ubiquitination-Mediated Gene SilencingR01GM130696 · NIGMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI WANG, HENGBIN · 2019 to 2020
$593k
NIGMS NIH HHS R01 GM130696
6 · The paper itself

Abstract

Meiosis is a specialized cell division that creates haploid germ cells from diploid progenitors. Through differential RNA expression analyses, we previously identified a number of mouse genes that were dramatically elevated in spermatocytes, relative to their very low expression in spermatogonia and somatic organs. Here, we investigated in detail

Indexed as

MeiosisPachytene StageSpermatogenesisAnimalsChromosome PairingDNA RepairFemaleInfertility, MaleMaleMiceMice, Inbred C57BLMice, KnockoutNuclear ProteinsSex ChromosomesSpermatocytesNuclear Proteinsmale germline-specific proteinMAPSmeiosis prophase Ipachynema progression

Identifiers

PMID33602822
PMCPMC7923350
OpenAlexW3131646350

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.