Evidence map›Paper›PMID 33602812›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Emergence of diauxie as an optimal growth strategy under resource allocation constraints in cellular metabolism.

Pierre Salvy, Vassily Hatzimanikatis

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
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  10. Actionable Forecasting as a Determinant of Biological Adaptation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  11. Article
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  14. From microbiome composition to functional engineering, one step at a time.Microbiology and molecular biology reviews : MMBR · 2023
    Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pierre SalvyLaboratory of Computational Systems Biotechnology, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.ORCID 0000-0002-3834-0356
Vassily HatzimanikatisLaboratory of Computational Systems Biotechnology, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland vassily.hatzimanikatis@epfl.ch.
École Polytechnique Fédérale de Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diauxie, or the sequential consumption of carbohydrates in bacteria such as

Indexed as

Metabolic Networks and PathwaysModels, BiologicalAcetatesEnzymesEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialGenome, BacterialGlucoseKineticsLactoseThermodynamicsAcetatesEnzymesEscherichia coli ProteinsGlucoseLactosediauxiedynamic FBAiterativeME modelsresource allocation

Identifiers

PMID33602812
PMCPMC7923608
OpenAlexW3130461562

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.