Evidence map›Paper›PMID 33602809›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

The DUF1013 protein TrcR tracks with RNA polymerase to control the bacterial cell cycle and protect against antibiotics.

Marie Delaby, Lydia M Varesio, Laurence Degeorges, Sean Crosson, Patrick H Viollier

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Marie DelabyDepartment of Microbiology and Molecular Medicine, Faculty of Medicine/Centre Médical Universitaire, University of Geneva, 1211 Genève 4, Switzerland.ORCID 0000-0001-5293-2449
Lydia M VaresioCommittee on Microbiology, University of Chicago, Chicago, IL 60637.ORCID 0000-0001-6394-1607
Laurence DegeorgesDepartment of Microbiology and Molecular Medicine, Faculty of Medicine/Centre Médical Universitaire, University of Geneva, 1211 Genève 4, Switzerland.
Sean CrossonDepartment of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824.ORCID 0000-0002-1727-322X
Patrick H ViollierDepartment of Microbiology and Molecular Medicine, Faculty of Medicine/Centre Médical Universitaire, University of Geneva, 1211 Genève 4, Switzerland; patrick.viollier@unige.ch.ORCID 0000-0002-5249-9910
University of Geneva · CHMichigan State University · USUniversity of Chicago · US

Funding

Molecular mechanisms controlling stress responses and cell adhesion in bacteriaR35GM131762 · NIGMS · MICHIGAN STATE UNIVERSITY · PI Sean Crosson · 2019 to 2026
$3.2M
Molecular mechanism of general stress signaling in Brucella abortusR01AI107159 · NIAID · UNIVERSITY OF CHICAGO · PI CROSSON, SEAN · 2014 to 2018
$2.2M
NIAID NIH HHS R01 AI107159NIGMS NIH HHS R35 GM131762
6 · The paper itself

Abstract

How DNA-dependent RNA polymerase (RNAP) acts on bacterial cell cycle progression during transcription elongation is poorly investigated. A forward genetic selection for

Indexed as

Anti-Bacterial AgentsBacterial ProteinsCaulobacter crescentusCell CycleDNA-Directed RNA PolymerasesGene Expression Regulation, BacterialPromoter Regions, GeneticAnti-Bacterial AgentsBacterial ProteinsDNA-Directed RNA PolymerasesBrucellaCaulobacterRNA polymerasetranscriptionTrcR

Identifiers

PMID33602809
PMCPMC7923619
OpenAlexW3132250170

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.