ArticleAJNR. American journal of neuroradiology2021
Inversion Recovery Ultrashort TE MR Imaging of Myelin is Significantly Correlated with Disability in Patients with Multiple Sclerosis.
Article in AJNR. American journal of neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Design of Differential Single-Block and Multi-Block Presaturated Ultrashort Echo Time Pulse Sequences for Fast and Flexible Short-TMagnetic resonance in medicine · 2026Article
- Motion-robust myelin imaging in MRI using 1D projection gating.Scientific reports · 2026Article
- Enhancing the Visibility of Multiple Sclerosis Lesions using Fused Images of Fluid Attenuated Inversion Recovery (FLAIR) and white matter Attenuated Inversion Recovery (WAIR) MRI Sequences.Current medical imaging · 2026Article
- Motion-Robust Direct Myelin Imaging in MRI using Self-Gating.Research square · 2025Article
- Brain short TNeuroImage · 2025Article
- Ultrashort Echo Time and Zero Echo Time MRI and Their Applications at High Magnetic Fields: A Literature Survey.Investigative magnetic resonance imaging · 2024Article
- Cerebrovascular markers of WMH and infarcts in ADNI: A historical perspective and future directions.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Review
- Clinical evaluation of white matter lesions on 3D inversion recovery ultrashort echo time MRI in multiple sclerosis.Quantitative imaging in medicine and surgery · 2023Article
- Quantitative myelin imaging with MRI and PET: an overview of techniques and their validation status.Brain : a journal of neurology · 2023Review
- Detection of iron oxide nanoparticle (IONP)-labeled stem cells using quantitative ultrashort echo time imaging: a feasibility study.Quantitative imaging in medicine and surgery · 2023Article
- The signal intensity variation of multiple sclerosis (MS) lesions on magnetic resonance imaging (MRI) as a potential biomarker for patients' disability: A feasibility study.Frontiers in neuroscience · 2023Article
- Autoimmune diseases of the brain, imaging and clinical review.The neuroradiology journal · 2022Review
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Authors and funding
9 authors.
Funding
Abstract
background and purposeMR imaging has been widely used for the noninvasive evaluation of MS. Although clinical MR imaging sequences are highly effective in showing focal macroscopic tissue abnormalities in the brains of patients with MS, they are not specific to myelin and correlate poorly with disability. We investigated direct imaging of myelin using a 2D adiabatic inversion recovery ultrashort TE sequence to determine its value in assessing disability in MS. MATERIALS AND
methodsThe 2D inversion recovery ultrashort TE sequence was evaluated in 14 healthy volunteers and 31 patients with MS. MPRAGE and T2-FLAIR images were acquired for comparison. Advanced Normalization Tools were used to correlate inversion recovery ultrashort TE, MPRAGE, and T2-FLAIR images with disability assessed by the Expanded Disability Status Scale.
resultsWeak correlations were observed between normal-appearing white matter volume (
conclusionsDirect imaging of myelin correlates with disability in patients with MS better than indirect imaging of long-T2 water in WM using conventional clinical sequences.
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