ArticleCurrent topics in developmental biology2021
Animal development in the microbial world: Re-thinking the conceptual framework.
Article in Current topics in developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 41 citations in OpenAlex.
- Harnessing the Microbiome in Cancer Immunotherapy: Regulation, Prediction, and Therapeutic Targeting.Annual review of immunology · 2026Review
- Environmental Microbial Cues Alter Embryonic Development and Stress Responses in Vertebrates: Insights From the Zebrafish (Danio rerio) Model.Molecular ecology · 2025Article
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- Diversity of the surface microbiome of canopy-forming brown macroalgae (Fucales) in the northern Adriatic.Microbiology spectrum · 2025Article
- Neonatal fungi promote lifelong metabolic health through macrophage-dependent β cell development.Science (New York, N.Y.) · 2025Article
- Evolution of the ocular immune system.Eye (London, England) · 2025Review
- ThemBio · 2025Article
- Transcriptomic responses of Mediterranean sponges upon encounter with symbiont microbial consortia.BMC genomics · 2024Article
- Intestinal dual-specificity phosphatase 6 regulates the cold-induced gut microbiota remodeling to promote white adipose browning.NPJ biofilms and microbiomes · 2024Article
- Inter-comparison of marine microbiome sampling protocols.ISME communications · 2023Article
- Article
- Potential for host-symbiont communication via neurotransmitters and neuromodulators in an aneural animal, the marine spongeFrontiers in neural circuits · 2023Article
- Contribution of Maternal and Paternal Transmission to Bacterial Colonization inFrontiers in microbiology · 2021Article
- Bacterial Communities Associated With Four Blooming Scyphozoan Jellyfish: Potential Species-Specific Consequences for Marine Organisms and Humans Health.Frontiers in microbiology · 2021Article
- SecretedGut microbesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Animals have evolved within the framework of the microbes and are constantly exposed to diverse microbiota. This dominance of the microbial world is forcing all fields of biology to question some of their most basic premises, with developmental biology being no exception. While animals under laboratory conditions can develop and live without microbes, they are far from normal, and would not survive under natural conditions, where their fitness would be strongly compromised. Since much of the undescribed biodiversity on Earth is microbial, any consideration of animal development in the absence of the recognition of microbes will be incomplete. Here, we show that animal development may never have been autonomous, rather it requires transient or persistent interactions with the microbial world. We propose that to formulate a comprehensive understanding of embryogenesis and post-embryonic development, we must recognize that symbiotic microbes provide important developmental signals and contribute in significant ways to phenotype production. This offers limitless opportunities for the field of developmental biology to expand.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.