Evidence map›Paper›PMID 33602354›Full record

ArticlePublic health nutrition2021

Dietary fluoride intake over the course of pregnancy in Mexican women.

Gina A Castiblanco-Rubio, Teresa V Muñoz-Rocha, Alejandra Cantoral, Martha M Téllez-Rojo, Adrienne S Ettinger, Adriana Mercado-García, Karen E Peterson, Howard Hu, Esperanza A Martínez-Mier

Open access · bronzeAbstract read
In one paragraph

Article in Public health nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Gina A Castiblanco-RubioDepartment of Cariology, Operative Dentistry and Dental Public Health, Indiana University, School of Dentistry, 415 Lansing St, Indianapolis, IN46202, USA.ORCID 0000-0002-4451-9563
Teresa V Muñoz-RochaCenter for Nutrition and Health Research, Instituto Nacional de Salud Pública de México (INSP), Cuernavaca, México.
Alejandra CantoralCenter for Nutrition and Health Research, Instituto Nacional de Salud Pública de México (INSP), Cuernavaca, México.
Martha M Téllez-RojoCenter for Nutrition and Health Research, Instituto Nacional de Salud Pública de México (INSP), Cuernavaca, México.
Adrienne S EttingerDepartment of Nutritional Sciences, University of Michigan, School of Public Health, Ann Arbor, MI, USA.
Adriana Mercado-GarcíaCenter for Nutrition and Health Research, Instituto Nacional de Salud Pública de México (INSP), Cuernavaca, México.
Karen E PetersonDepartment of Nutritional Sciences, University of Michigan, School of Public Health, Ann Arbor, MI, USA.
Howard HuUniversity of Washington, School of Public Health, Seattle, WA, USA.
Esperanza A Martínez-MierDepartment of Cariology, Operative Dentistry and Dental Public Health, Indiana University, School of Dentistry, 415 Lansing St, Indianapolis, IN46202, USA.
Instituto Nacional de Salud Pública · MXIndiana University – Purdue University Indianapolis · USRutgers, The State University of New Jersey · USUniversity of Michigan · USUniversity of Washington · US

Funding

Project 3: Developmental Exposures and Diet: Epigenetics of Metabolic SyndromeP01ES022844 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DOLINOY, DANA, PADMANABHAN, VASANTHA · 2013 to 2018
$3.9M
Prenatal and Childhood Exposure to Fluoride and NeurodevelopmentR01ES021446 · NIEHS · UNIVERSITY OF TORONTO · PI HU, HOWARD, MCLAUGHLIN, JOHN · 2012 to 2018
$2.3M
NIEHS NIH HHS P01 ES022844NIEHS NIH HHS R01 ES021446
6 · The paper itself

Abstract

objectiveTo estimate dietary fluoride intake (F) over the course of pregnancy and the overall adjusted difference in dietary F intake by pregnancy stages and levels of compliance with dietary recommendations.

designSecondary data analysis from a longitudinal pregnancy cohort study in a population exposed to fluoridated salt. Women were followed during the early, middle and late stages of their pregnancy (n 568). The dietary intake of recommended prenatal nutrients according to Mexican dietary guidelines and F intake (mg/d) was estimated with a validated FFQ. Data were summarised with descriptive statistics. Levels of F intake were compared with the USA's Institute of Medicine adequate intake (AI) of 3 mg/d for pregnancy. Adjusted differences in F intake by pregnancy stages and levels of compliance with recommendations were estimated using random effects models.

settingMexico City.

participantsWomen participating in the Early Life Exposures in Mexico to ENvironmental Toxicants (ELEMENT) project, from 2001 to 2003.

resultsMedian dietary F intake throughout pregnancy ranged from 0·64 (interquartile range (IQR) 0·38) in the early to 0·70 (IQR 0·42) in the middle, and 0·72 (IQR 0·44) mg/d in the late stage (0·01 mg F/kg per d). Corresponding adjusted intakes of F were 0·72 (95 % CI 0·70, 0·74), 0·76 (95 % CI 0·74, 0·77) and 0·80 (95 % CI 0·78, 0·82) mg/d. Women who were moderately and highly compliant with Mexican dietary recommendations ingested, on average, 0·04 and 0·14 mg F/d more than non-compliant women (P < 0·005).

conclusionsDietary F intake was below current AI, was greater with the progression of pregnancy and in women who were moderately and highly compliant with dietary recommendations.

Indexed as

DietFluoridesCohort StudiesFemaleHumansMexicoNutrition PolicyPregnancyFluoridesDietary exposureFluoridePregnancyPrenatal exposure

Identifiers

PMID33602354
PMCPMC10195551
OpenAlexW3130184536

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.