Evidence map›Paper›PMID 33602342›Full record

ArticleJournal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale2021

Visual biofeedback for paradoxical vocal fold motion (PVFM).

Rachelle Alyce LeBlanc, Daniel Aalto, Caroline C Jeffery

Registry-linked trialOpen access · goldAbstract readClinical Study
In one paragraph

Article in Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05770518 (Biofeedback vs Laryngeal Control Therapy in Management of Paradoxical Vocal Fold Motion), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05770518 nacompletednot on this mapstarted 2023, after this paper: background citation

Biofeedback vs Laryngeal Control Therapy in Management of Paradoxical Vocal Fold Motion (BLiMP)

TypeinterventionalSponsorWashington University School of MedicineRan2023 to 2024Enrolled51ConditionsParadoxical Vocal Fold Motion, Vocal Cord DysfunctionArmsBiofeedback, Laryngeal control therapy (LCT)
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Trauma-Informed Care for Voice, Airway, and Swallowing Disorders: A Scoping Review.ORL-head and neck nursing : official journal of the Society of Otorhinolaryngology and Head-Neck Nurses · 2026
    Article
  3. Article
  4. Clinical Case Study: Pediatric Exercise-Induced Laryngeal Obstruction.Perspectives of the ASHA special interest groups · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. A Scoping Review to Map Health Outcomes in Inducible Laryngeal Obstruction.International journal of language & communication disorders
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rachelle Alyce LeBlancDivision of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Alberta, 1E4 Walter Mackenzie Centre, 8440-112 Street NW, Edmonton, Alberta, T6G 2B7, Canada.
Daniel AaltoFaculty of Rehabilitation Medicine, University of Alberta, Edmonton, Alberta, Canada.
Caroline C JefferyDivision of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Alberta, 1E4 Walter Mackenzie Centre, 8440-112 Street NW, Edmonton, Alberta, T6G 2B7, Canada. caroline.jeffery@ahs.ca.ORCID http://orcid.org/0000-0002-5536-4915
University of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesParadoxical vocal fold motion (PVFM) is a common condition where the vocal folds inappropriately adduct during inspiration. This results in dyspnea and occasionally significant distress. The condition is thought to be primarily functional, with behavioural therapy considered mainstay in the non-acute setting. However, practice variations and limited access to speech language pathology (SLP) services can pose management challenges. We aimed to examine the efficacy of surgeon performed visual biofeedback as first-line treatment for PVFM. STUDY

designProspective, non-randomized, non-comparative clinical study.

methodsAdult patients referred for possible PVFM and congruent laryngoscopy findings over a two-year period were included. Patients were excluded if they presented in acute distress, had alternate diagnosis to explain symptomology and/or coexisting untreated lower respiratory pathology. Patients underwent immediate surgeon-performed visual biofeedback on the same visit day. The primary outcome of interest was change in Dyspnea Index (DI) scores pre- and post-intervention 3 months follow-up. The secondary outcome measured was change in asthma medication use from baseline to follow-up.

resultsOf 34 patients presenting, 25 met inclusion criteria. Of these, 72% were female with an average age of 36.9 ± 14.1. Approximately 48% of patients had a diagnosis of well-controlled asthma at presentation and co-morbid psychiatric diagnoses were common (52%). Pre- and post-intervention analysis showed significant improvement in DI scores (p < 0.001) and reduction in bronchodilator use (p = 0.003).

conclusionThis is a prospective study that evaluates the role of visual biofeedback in PVFM patients. Our data suggests that visual biofeedback effectively reduces short-term subjective symptoms and asthma medication use. LEVEL OF EVIDENCE: 3.

Indexed as

Biofeedback, PsychologyVisual PerceptionAdultFemaleHumansMaleProspective StudiesVocal Cord DysfunctionBiofeedbackParadoxical vocal fold motion

Identifiers

PMID33602342
PMCPMC7891140
OpenAlexW3133043695

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.