ReviewTrials2021
COVID-19 trials: declarations of data sharing intentions at trial registration and at publication.
Review in Trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Features and results availability of non-commercial Spanish COVID-19 trials: a systematic review of clinical trial registers and corresponding literature.European journal of clinical pharmacology · 2025Pooled it
- Practice of data sharing plans in clinical trial registrations and concordance between registered and published data sharing plans: a cross-sectional study.BMC medicine · 2025Article
- Evaluating the discoverability of supporting research materials in ClinicalTrials.gov for US federally funded COVID-19 clinical studies.Journal of the Medical Library Association : JMLA · 2024Article
- Exploration of registration and the risk of bias in acupuncture randomised controlled trials: a systematic review protocol.BMJ open · 2024Article
- An assessment of the informative value of data sharing statements in clinical trial registries.BMC medical research methodology · 2024Article
- Data sharing and reuse in clinical research: Are we there yet? A cross-sectional study on progress, challenges and opportunities in LMICs.PLOS global public health · 2024Article
- What motivates individuals to share information with governments when adopting health technologies during the COVID-19 pandemic?BMC public health · 2023Article
- ISO/TS 21564:2019- based Evaluation of a Semantic Map between Variables in the ISARIC Freestanding Follow Up Survey and ORCHESTRA Studies.Journal of medical systems · 2023Article
- Totality of evidence of the effectiveness of repurposed therapies for COVID-19: Can we use real-world studies alongside randomized controlled trials?Clinical and translational science · 2023Article
- Article
- Article
- Many researchers say they'll share data - but don't.Nature · 2022Article
- Regulatory Frameworks for Clinical Trial Data Sharing: Scoping Review.Journal of medical Internet research · 2022Article
- COVID-19 interventional trials: Analysis of data sharing intentions during a time of pandemic.Contemporary clinical trials · 2022Article
- Promotion of data sharing needs more than an emergency: An analysis of trends across clinical trials registered on the International Clinical Trials Registry Platform.Wellcome open research · 2022Article
- Open data and data sharing in articles about COVID-19 published in preprint servers medRxiv and bioRxiv.Scientometrics · 2022Article
- Open science saves lives: lessons from the COVID-19 pandemic.BMC medical research methodology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe sharing of individual participant-level data from COVID-19 trials would allow re-use and secondary analysis that can help accelerate the identification of effective treatments. The sharing of trial data is not the norm, but the unprecedented pandemic caused by SARS-CoV-2 may serve as an impetus for greater data sharing. We sought to assess the data sharing intentions of interventional COVID-19 trials as declared in trial registrations and publications.
methodsWe searched ClinicalTrials.gov and PubMed for COVID-19 interventional trials. We analyzed responses to ClinicalTrials.gov fields regarding intent to share individual participant level data and analyzed the data sharing statements in eligible publications.
resultsNine hundred twenty-four trial registrations were analyzed. 15.7% were willing to share, of which 38.6% were willing to share immediately upon publication of results. 47.6% declared they were not willing to share. Twenty-eight publications were analyzed representing 26 unique COVID-19 trials. Only seven publications contained data sharing statements; six indicated a willingness to share data whereas one indicated that data was not available for sharing.
conclusionsAt a time of pressing need for researchers to work together to combat a global pandemic, intent to share individual participant-level data from COVID-19 interventional trials is limited.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.