Evidence map›Paper›PMID 33602241›Full record

ArticleRespiratory research2021

Gender modifies the effect of body mass index on lung function decline in mild-to-moderate COPD patients: a pooled analysis.

Wenjia Chen, Mohsen Sadatsafavi, J Mark FitzGerald, Larry D Lynd, Don D Sin

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Prediction for the maximum inspiratory pressure value from the thoracic expansion measurement in Indonesian healthy young adults.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Wenjia ChenRespiratory Evaluation Sciences Program, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, 2405 Wesbrook Mall, Vancouver, BC, V6T 1Z3, Canada.
Mohsen SadatsafaviRespiratory Evaluation Sciences Program, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, 2405 Wesbrook Mall, Vancouver, BC, V6T 1Z3, Canada.
J Mark FitzGeraldDivision of Respiratory Medicine, Faculty of Medicine, The University of British Columbia, Vancouver, Canada.
Larry D LyndRespiratory Evaluation Sciences Program, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, 2405 Wesbrook Mall, Vancouver, BC, V6T 1Z3, Canada.
Don D SinUBC Centre for Heart Lung Innovation, St Paul's Hospital, Providence Building, Room 8446, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada. Don.Sin@hli.ubc.ca.
St. Paul's Hospital · CAUniversity of British Columbia · CAVancouver Coastal Health · CAVancouver Coastal Health Research Institute · CA

Funding

CIHR FDN-143226
6 · The paper itself

Abstract

backgroundLow body weight is associated with poor prognosis in patients with chronic obstructive pulmonary disease (COPD). However, it is not known whether gender modifies this relationship.

methodsWe pooled data of 8686 COPD patients from 7 studies with a median length of 36-months of follow up. Using a longitudinal natural cubic spline regression model, we examined the dose-response relationship between body mass index (BMI) and the rate of decline in forced expiratory volume in one second (FEV

resultsThere was an inverse linear relationship between BMI and the rate of FEV

conclusionIn mild to moderate COPD, higher BMI was associated with a less rapid decline of FEV

Indexed as

Body Mass IndexForecastingAgedBritish ColumbiaDisease ProgressionFemaleFollow-Up StudiesForced Expiratory VolumeHumansIncidenceLungMaleMiddle AgedProspective StudiesPulmonary Disease, Chronic ObstructiveRespiratory Function TestsBody mass indexCOPDFEV1Lung function decline

Identifiers

PMID33602241
PMCPMC7891012
OpenAlexW3122271644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.