ArticleBMC plant biology2021
Molecular cloning and characterization of GhERF105, a gene contributing to the regulation of gland formation in upland cotton (Gossypium hirsutum L.).
Article in BMC plant biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 24 citations in OpenAlex.
- Genome-wide identification and expression analysis of IDD gene family in Gossypium hirsutum L.Functional & integrative genomics · 2026Article
- TaERF109: A Novel ERF Transcription Factor Contributing to Enhanced Resistance toPathogens (Basel, Switzerland) · 2026Article
- Engineering seed-specific gossypol-free cotton for human-safe consumption by harnessing the dominant-negative effect of the GlPlant communications · 2026Article
- The Genetic Wiring of Plant Trichomes: From Initiation to Fate Specification.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Comparative single-cell transcriptomic map reveals divergence in leaves between two cotton species at cell type resolution.Journal of advanced research · 2026Article
- AP2/ERF transcription factors regulate the biosynthesis of terpenoids, phenolics, and alkaloids in plants.Horticulture research · 2026Article
- Article
- The GoSPGF-GoPGF-GhWRKYs transcriptional cascade positively regulates pigment gland formation in the stem of upland cotton.Plant biotechnology journal · 2025Article
- Article
- Ethylene Signaling in Regulating Plant Growth, Development, and Stress Responses.Plants (Basel, Switzerland) · 2025Review
- Single-cell transcriptome atlas identified novel regulators for pigment gland morphogenesis in cotton.Plant biotechnology journal · 2023Article
- Genome-wide investigation and expression profiles of theFrontiers in plant science · 2023Article
- Development of the engineered "glanded plant and glandless seed" cotton.Food chemistry. Molecular sciences · 2022Article
- Utilizing Nutritional and Polyphenolic Compounds in Underutilized Plant Seeds for Health Application.Molecules (Basel, Switzerland) · 2022Review
- An Overview of Cotton Gland Development and Its Transcriptional Regulation.International journal of molecular sciences · 2022Review
- Article
- Musashi-1-A Stemness RBP for Cancer Therapy?Biology · 2021Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundGossypium hirsutum L. (cotton) is one of the most economically important crops in the world due to its significant source of fiber, feed, foodstuff, oil and biofuel products. However, the utilization of cottonseed was limited due to the presence of small and darkly pigmented glands that contain large amounts of gossypol, which is toxic to human beings and non-ruminant animals. To date, some progress has been made in the pigment gland formation, but the underlying molecular mechanism of its formation was still unclear.
resultsIn this study, we identified an AP2/ERF transcription factor named GhERF105 (GH_A12G2166), which was involved in the regulation of gland pigmentation by the comparative transcriptome analysis of the leaf of glanded and glandless plants. It encoded an ERF protein containing a converved AP2 domain which was localized in the nucleus with transcriptional activity, and showed the high expression in glanded cotton accessions that contained much gossypol. Virus-induced gene silencing (VIGS) against GhERF105 caused the dramatic reduction in the number of glands and significantly lowered levels of gossypol in cotton leaves. GhERF105 showed the patterns of spatiotemporal and inducible expression in the glanded plants.
conclusionsThese results suggest that GhERF105 contributes to the pigment gland formation and gossypol biosynthesis in partial organs of glanded plant. It also provides a potential molecular basis to generate 'glandless-seed' and 'glanded-plant' cotton cultivar.
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