Evidence map›Paper›PMID 33601889›Full record

ArticleACS chemical biology2021

Natural Occurrence of Hybrid Polyketides from Two Distinct Biosynthetic Pathways in

Wei Zhou, Priyapan Posri, Taifo Mahmud

Open access · greenAbstract read
In one paragraph

Article in ACS chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Wei ZhouDepartment of Pharmaceutical Sciences, Oregon State University, Corvallis, Oregon 97331-3507, United States.ORCID 0000-0001-7540-2459
Priyapan PosriDepartment of Pharmaceutical Sciences, Oregon State University, Corvallis, Oregon 97331-3507, United States.ORCID 0000-0002-8035-2799
Taifo MahmudDepartment of Pharmaceutical Sciences, Oregon State University, Corvallis, Oregon 97331-3507, United States.ORCID 0000-0001-9639-526X
Oregon State University · US

Funding

Biosynthetic studies and development of ribomimetic-based anti-infectivesR01AI129957 · NIAID · OREGON STATE UNIVERSITY · PI MAHMUD, TAIFO · 2018 to 2022
$1.8M
Acquisition of a 700 MHz NMR SpectrometerS10OD018518 · OD · OREGON STATE UNIVERSITY · PI BARBAR, ELISAR J · 2015 to 2015
$1.3M
NIAID NIH HHS R01 AI129957NIH HHS S10 OD018518
6 · The paper itself

Abstract

Nature has always been seemingly limitless in its ability to create new chemical entities. It provides vastly diverse natural compounds through a biomanufacturing process that involves myriads of biosynthetic machineries. Here we report a case of unusual formations of hybrid natural products that are derived from two distinct polyketide biosynthetic pathways, the NFAT-133 and conglobatin pathways, in

Indexed as

Genes, BacterialMultigene FamilyPolyketidesPolyketide SynthasesProtein DomainsStreptomycesThiolester HydrolasesPolyketidesPolyketide SynthasesThiolester Hydrolases

Identifiers

PMID33601889
PMCPMC7932018
OpenAlexW3127601297

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.