Evidence map›Paper›PMID 33601712›Full record

ArticleJournal of affective disorders2021

Altered reward responsiveness and depressive symptoms: An examination of social and monetary reward domains and interactions with rejection sensitivity.

Samantha Pegg, Kodi B Arfer, Autumn Kujawa

Open access · greenAbstract read
In one paragraph

Article in Journal of affective disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Samantha PeggVanderbilt University, Department of Psychology and Human Development, United States.
Kodi B ArferMount Sinai Health System, Icahn School of Medicine, Department of Environmental Medicine and Public Health, United States.
Autumn KujawaVanderbilt University, Department of Psychology and Human Development, United States. Electronic address: autumn.kujawa@vanderbilt.edu.
Vanderbilt University · USMount Sinai Health System · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
LIFE-SPAN DEVELOPMENT OF NORMAL AND ABNORMAL BEHAVIORT32MH018921 · NIMH · VANDERBILT UNIVERSITY · PI HUMPHREYS, KATHRYN LEIGH · 1989 to 2024
$6.7M
NCATS NIH HHS UL1 TR000445NIMH NIH HHS T32 MH018921
6 · The paper itself

Abstract

backgroundAlterations in positive valence systems and social processes, including low reward responsiveness and high rejection sensitivity, have been observed in depression. Most reward research focuses on the monetary domain, but social reward responsiveness may be particularly relevant to understanding the etiology of depression, especially in combination with other social processes. Pathways to depression are complex, and research testing interactions between multiple factors is needed. The present study examined the interactive effects of reward responsiveness and rejection sensitivity on depressive symptoms using both social and monetary reward electroencephalogram (EEG) tasks.

methodsEmerging adults (N = 120) completed peer interaction and monetary incentive delay tasks while EEG data were recorded, as well as self-report measures of rejection sensitivity and depressive symptoms.

resultsThe interaction between social reward responsiveness and self-reported rejection sensitivity was significantly associated with depressive symptoms, such that rejection sensitivity was associated with greater depressive symptoms for those with a relatively reduced response to social reward. The interaction between monetary reward responsiveness and rejection sensitivity was not significant. LIMITATIONS: The study was cross-sectional and used a non-clinical sample.

conclusionsResults suggest a possible pathway for depressive symptoms characterized by the combination of high rejection sensitivity and low social reward responsiveness. Findings highlight the need for consideration of multiple domains of reward responsiveness in clinical neuroscience research. With extension to longitudinal studies and clinical samples, the present findings may inform understanding of targets for intervention.

Indexed as

DepressionEvoked PotentialsAdultCross-Sectional StudiesHumansMotivationRewardDepressionEvent-related potentialsNeurophysiologyRejection sensitivityReward

Identifiers

PMID33601712
PMCPMC7896043
OpenAlexW3116295582

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.