Evidence map›Paper›PMID 33601544›Full record

ArticlePhysical review. E2021

Trapping of particles diffusing in two dimensions by a hidden binding site.

Leonardo Dagdug, Alexander M Berezhkovskii, Vladimir Yu Zitserman, Sergey M Bezrukov

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physical review. E, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Leonardo DagdugDepartamento de Fisica, Universidad Autonoma Metropolitana-Iztapalapa, 09340 Mexico City, Mexico.
Alexander M BerezhkovskiiMathematical and Statistical Computing Laboratory, Office of Intramural Research, Center for Information Technology, National Institutes of Health, Bethesda, Maryland 20819, USA.
Vladimir Yu ZitsermanJoint Institute for High temperatures, Russian Academy of Sciences, Izhorskaya 13, Building 2, Moscow 125412, Russia.
Sergey M BezrukovSection of Molecular Transport, Eunice Kennedy Shriver National Institute of Child health and Human Development, National Institutes of Health, Bethesda, Maryland 20819, USA.

Funding

Biophysics of Large Membrane ChannelsZIAHD000072 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI BEZRUKOV, SERGEY M · 2009 to 2025
$22.8M
Modeling of kinetic processes in biological systemsZIACT000273 · CIT · CENTER FOR INFORMATION TECHNOLOGY · PI BEREZHKOVSKII, ALEXANDER · 2009 to 2021
$2.1M
Intramural NIH HHS ZIA HD000072
6 · The paper itself

Abstract

We study trapping of particles diffusing in a two-dimensional rectangular chamber by a binding site located at the end of a rectangular sleeve. To reach the site a particle first has to enter the sleeve. After that it has two options: to come back to the chamber or to diffuse to the site where it is trapped. The main result of the present work is a simple expression for the mean particle lifetime as a function of its starting position and geometric parameters of the system. This expression is obtained by an approximate reduction of the initial two-dimensional problem to the effective one-dimensional one which can be solved with relative ease. Our analytical predictions are tested against the results obtained from Brownian dynamics simulations. The test shows excellent agreement between the two for a wide range of the geometric parameters of the system.

Identifiers

PMID33601544
PMCPMC9006174

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.